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ATP-binding cassette sub-family C member 5

Summary

UniProt ID: Q9QYM0
Gene Symbol: Abcc5 Mrp5
Gene ID: 116721
Organism: Rattus norvegicus (Norway rat)

External Links

PubChem: Q9QYM0
Re-Glyco: Q9QYM0

Annotation

Keyword: ATP-binding Cell membrane Endosome Glycoprotein Golgi apparatus Phosphoprotein Reference proteome Repeat Translocase Transmembrane helix Transport

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	Reference
purine nucleotide transport	ISO	GO_REF
hyaluronan biosynthetic process	ISO	GO_REF
response to lipopolysaccharide	IEP	PMID
response to insulin	IEP	PMID
glutathione transmembrane transport	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

hyaluronan metabolic process [inference]

hyaluronan biosynthetic process

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

hyaluronan metabolic process [inference]

hyaluronan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

hyaluronan biosynthetic process

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

heme transmembrane transport

vitamin transmembrane transport [inference]

folate transmembrane transport

oligopeptide transmembrane transport [inference]

tripeptide transmembrane transport [inference]

glutathione transmembrane transport

export across plasma membrane

carboxylic acid transmembrane transport [inference]

folate transmembrane transport

export from cell [inference]

export across plasma membrane

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to chemical [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to lipid [inference]

response to lipopolysaccharide

response to nitrogen compound [inference]

response to peptide hormone [inference]

response to insulin

response to oxygen-containing compound [inference]

response to lipopolysaccharide

response to peptide hormone [inference]

response to insulin

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

iron ion transport [inference]

iron ion transmembrane transport [inference]

heme transmembrane transport

iron coordination entity transport [inference]

heme transport [inference]

heme transmembrane transport

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

heme transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

heme transmembrane transport

organic anion transport [inference]

glutathione transport [inference]

glutathione transmembrane transport

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

folic acid transport [inference]

folate transmembrane transport

carboxylic acid transmembrane transport [inference]

folate transmembrane transport

organophosphate ester transport [inference]

nucleotide transport [inference]

purine nucleotide transport

guanine nucleotide transport [inference]

cGMP transport

purine ribonucleotide transport [inference]

adenine nucleotide transport [inference]

cAMP transport

cyclic nucleotide transport [inference]

peptide transport [inference]

oligopeptide transport [inference]

oligopeptide transmembrane transport [inference]

tripeptide transmembrane transport [inference]

glutathione transmembrane transport

tripeptide transport [inference]

glutathione transport [inference]

glutathione transmembrane transport

tripeptide transmembrane transport [inference]

glutathione transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

folic acid transport [inference]

folate transmembrane transport

carboxylic acid transmembrane transport [inference]

folate transmembrane transport

xenobiotic transport

vitamin transport [inference]

folic acid transport [inference]

folate transmembrane transport

vitamin transmembrane transport [inference]

folate transmembrane transport

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

heme transmembrane transport

vitamin transmembrane transport [inference]

folate transmembrane transport

oligopeptide transmembrane transport [inference]

tripeptide transmembrane transport [inference]

glutathione transmembrane transport

export across plasma membrane

carboxylic acid transmembrane transport [inference]

folate transmembrane transport

nitrogen compound transport [inference]

oligopeptide transport [inference]

oligopeptide transmembrane transport [inference]

tripeptide transmembrane transport [inference]

glutathione transmembrane transport

tripeptide transport [inference]

glutathione transport [inference]

glutathione transmembrane transport

tripeptide transmembrane transport [inference]

glutathione transmembrane transport

heme transport [inference]

heme transmembrane transport

nucleobase-containing compound transport [inference]

nucleotide transport [inference]

purine nucleotide transport

guanine nucleotide transport [inference]

cGMP transport

purine ribonucleotide transport [inference]

adenine nucleotide transport [inference]

cAMP transport

cyclic nucleotide transport [inference]

modified amino acid transport [inference]

folic acid transport [inference]

folate transmembrane transport

glutathione transport [inference]

glutathione transmembrane transport

sulfur compound transport [inference]

glutathione transport [inference]

glutathione transmembrane transport

export from cell [inference]

export across plasma membrane

carbohydrate derivative transport [inference]

purine ribonucleotide transport [inference]

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	Reference
Golgi lumen	ISS	GO_REF
Golgi lumen	ISO	GO_REF
Golgi lumen	IEA	GO_REF
plasma membrane	ISO	GO_REF
endosome membrane	ISS	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

plasma membrane region [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

Golgi lumen

perinuclear region of cytoplasm

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	Reference
ATP binding	IEA	GO_REF
ABC-type xenobiotic transporter activity	ISS	GO_REF
ABC-type xenobiotic transporter activity	ISO	GO_REF
ABC-type xenobiotic transporter activity	IEA	GO_REF
purine nucleotide transmembrane transporter activity	ISO	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

transmembrane transporter activity [inference]

organophosphate ester transmembrane transporter activity [inference]

nucleotide transmembrane transporter activity [inference]

purine nucleotide transmembrane transporter activity

nucleobase-containing compound transmembrane transporter activity [inference]

nucleotide transmembrane transporter activity [inference]

purine nucleotide transmembrane transporter activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity

ABC-type xenobiotic transporter activity

macromolecule transmembrane transporter activity

oligopeptide transmembrane transporter activity [inference]

tripeptide transmembrane transporter activity [inference]

glutathione transmembrane transporter activity

xenobiotic transmembrane transporter activity

ABC-type xenobiotic transporter activity

modified amino acid transmembrane transporter activity [inference]

glutathione transmembrane transporter activity

carbohydrate derivative transmembrane transporter activity

sulfur compound transmembrane transporter activity [inference]

glutathione transmembrane transporter activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity

ABC-type xenobiotic transporter activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MKDIDMGKEYIIPSPGYRSVRDRSTIPGTHGDREDPSSGEQISLECQDALETAARVEGLSLDISVHSHLQILDEEHTKGKYHHGLSALKPFRTTTKHQHPVDNAGLFSYMTFSWLSPLAQVVHKKGELLMEDVWPLSKYESSDVNCRRLERLWQEELNEVGPDAASLRRVVWIFCRTRLILSIVCLMITQLAGFSGPAFVVKHLLEYTQATESNLQYSLLLVLGLLLTEVVRSWSLALTWALNYRTGVRLRGAVLTMAFKKILKLKNIKEKSLGELINICSNDGQRMFEAAAVGSLLAGGPVVAILGMIYNVIILGPTGFLGSAVFILFYPAMMFVSRLTAYFRRKCVAATDDRVQKMNEVLTYIKFIKMYAWVKAFSQCVQKIREEERRILEKAGYFQSITVGVAPIVVVIASVVTFSVHMTLGFDLTAAQAFTVVTVFNSMTFALKVTPFSVKSLSEASVAVDRFKSLFLMEEVHMIKNKPASPHIKIEMKNATLAWDSSHSSTQSSPKLTPKVKKDKRAPKGKKEKSRQLQHTEHQAVLAEQKGHLLLDSDERPSPEEEEGKQIHAGSMRLQRTLYNIDLEIEEGKLVGICGSVGSGKTSLISAILGQMTLLEGSIAVSGTFAYVAQQAWILNATLRDNILFGKEFDEERYNSVLNSCCLRPDLAILPNSDLTEIGERGANLSGGQRQRISLARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKRLKSKTVLFVTHQLQYLVDCDEVIFMKEGCITERGTHEELMNLNGDYATIFNNLLLGETPPVEINSKKEASGSQKSQDKGPKPGSVKKEKAVKSEEGQLVQVEEKGQGSVPWSVYWVYIQAAGGPLAFLVIMVLFMLNVGSTAFSTWWLSYWIKQGSGNSTVFEGNRSSVSDSMRDNPFLQYYASIYALSMAVMLILKAIRGVVFVKGTLRASSRLHDELFRRILRSPMKFFDTTPTGRILNRFSKDMDEVDVRLPFQAEMFIQNVILVFFCVGMIAGVFPWFLVAVGPLLILFSVLHIVSRVLIRELKRLDNITQSPFLSHITSSIQGLATIHAYNKRQEFLHRYQELLDDNQAPFFLFTCAMRWLAVRLDLISIALITTTGLMIVLMHGQIPSAYAGLAISYAVQLTGLFQFTVRLASETEARFTSVERINHYIKTLSLEAPARIKNKAPPHDWPQEGEITFENAEMRYRENLPLVLKKVSFTIKPKEKIGIVGRTGSGKSSLGMALFRLVELSGGCIKIDGVRISDIGLADLRSKLAIIPQEPVLFSGTVRSNLDPFNQYTEEQIWDALERTHMKECIAQLPLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDTETDLLIQETIREAFADCTMLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLLSNDSSRFYAMCAAAENKVAVKG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	Source
494	N-linked (GlcNAc...) asparagine	UniProt
636	N-linked (GlcNAc...) asparagine	UniProt
684	N-linked (GlcNAc...) asparagine	UniProt
889	N-linked (GlcNAc...) asparagine	UniProt
896	N-linked (GlcNAc...) asparagine	UniProt
1043	N-linked (GlcNAc...) asparagine	UniProt
1328	N-linked (GlcNAc...) asparagine	UniProt
1416	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
ABC-family protein mediated transport	Rattus norvegicus
APAP ADME	Rattus norvegicus
Azathioprine ADME	Rattus norvegicus
Hyaluronan metabolism	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

International Collaboration

Acknowledgements