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Frizzled-4

Summary

UniProt ID

Q9QZH0

Gene Symbol

Fzd4

Gene ID

64558

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q9QZH0
Re-Glyco: Q9QZH0

Annotation

Keyword

Cell membrane
Developmental protein
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Signal
Transmembrane helix
Ubl conjugation
Wnt signaling pathway

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
plasma membrane
cell-cell junction
dendrite
synapse
cell surface
glutamatergic synapse

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 30 in total

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GO Term
extracellular matrix-cell signaling
progesterone secretion
retina vasculature morphogenesis in camera-type eye
retinal blood vessel morphogenesis
Norrin signaling pathway
positive regulation of neuron projection arborization
Wnt signaling pathway, calcium modulating pathway
substrate adhesion-dependent cell spreading
angiogenesis
blood vessel development

Displaying entries **1 - 10** of 12 in total

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GO Term
G protein-coupled receptor activity
signaling receptor activity
Wnt-protein binding
amyloid-beta binding
cytokine receptor activity
cytokine binding
ubiquitin protein ligase binding
protein homodimerization activity
Wnt receptor activity
protein-containing complex binding

Annotation information from UniProt.

Sequence

MAWQGTGPSVRGMPGGVRLRLGLLLLQLLLLQRPALGFGDEEERRCDPIRIAMCQNLGYNVTKMPNLVGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLKEFGFAWPDSLNCSKFPPQNDHNHMCMEGPGDEEVPLPHKTPIQPGEECHSVGTNSDQYIWVKRSLNCVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTTFTVLTFLIDSSRFSYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEEAAEPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQSLDALTGFVVAPLFTYLVIGTLFIAAGLVALFKIRSNLQKDGTKTDKLERLMVKIGVFSVLYTVPATCVIACYFYEISNWALFRYSADDSNMAVEMLKIFMSLLVGITSGMWIWSAKTLHTWQKCSNRLVNSGKVKREKRGNGWVKPGKGNETVV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
60	N-linked (GlcNAc...) asparagine	UniProt
145	N-linked (GlcNAc...) asparagine	UniProt
382	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Asymmetric localization of PCP proteins	Rattus norvegicus
Ca2+ pathway	Rattus norvegicus
Cargo recognition for clathrin-mediated endocytosis	Rattus norvegicus
Clathrin-mediated endocytosis	Rattus norvegicus
Regulation of FZD by ubiquitination	Rattus norvegicus
WNT5A-dependent internalization of FZD4	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements