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Disintegrin and metalloproteinase domain-containing protein 11

Summary

UniProt ID: Q9R1V4
Gene Symbol: Adam11 Mdc
Gene ID: 11488
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q9R1V4
PubChem: Q9R1V4
The O-GlcNAc Database: Q9R1V4
Re-Glyco: Q9R1V4

Annotation

Keyword: Cell membrane Cell projection Cleavage on pair of basic residues Disulfide bond EGF-like domain Glycoprotein Reference proteome Signal Synapse Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	Reference
proteolysis	IBA	GO_REF
proteolysis	IEA	GO_REF
multicellular organismal response to stress	IMP	PMID
establishment of protein localization	IMP	PMID
behavioral response to acetic acid induced pain	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

multicellular organismal process [inference]

behavior [inference]

chemosensory behavior [inference]

behavioral response to chemical pain [inference]

behavioral response to pain [inference]

behavioral response to chemical pain [inference]

multicellular organismal response to stress

response to pain [inference]

behavioral response to pain [inference]

behavioral response to chemical pain [inference]

response to stimulus [inference]

response to stress [inference]

multicellular organismal response to stress

response to pain [inference]

behavioral response to pain [inference]

behavioral response to chemical pain [inference]

localization [inference]

establishment of localization [inference]

establishment of protein localization

Displaying **all 5** entries
GO Term	Evidence Code	Reference
axon	IEA	GO_REF
presynaptic membrane	EXP	PMID
presynaptic membrane	IEA	GO_REF
perikaryon	EXP	PMID
perikaryon	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

perikaryon

Displaying **all 2** entries
GO Term	Evidence Code	Reference
metalloendopeptidase activity	IBA	GO_REF
metalloendopeptidase activity	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MRRLRRWAIAALLLLPLLPPPGLGALGPRGALHWRSSAHVGSPESPEGSEVTEPSRLVRQSSGGEVRKPQLDTRVRQDPPRGTPVHLAQVSFVIPAFDSNFTLDLELNHHLLSSQYVERHFSREGTRQHSTGAGDHCYYHGKLRGNPQSFAALSTCQGLHGVFSDGNLTYIVEPKEIAGPWGPPQGPLPHLIYRTPLLPAPLGCREPGCLFAVPAQSALPNWPKLRRKRQVRRGHPTVHSETKYVELIVINDHQLFEQMRQSVVLTSNFAKSVVNLADVIYKEQLNTRIVLVAMETWADGDKIQVQDDLLETLARLMVYRREGLPEPSDATHLFSGRTFQSTSSGAAYVGGICSLSRGGGVNEYGNMGAMAVTLAQTLGQNLGMMWNKHRSSAGDCKCPDIWLGCIMEDTGFYLPRKFSRCSIDEYNQFLQEGGGSCLFNKPLKLLDPPECGNGFVEAGEECDCGSVQECSRAGGNCCKKCTLTHDAMCSDGLCCRRCKYEPRGVSCREAVNECDIAETCTGDSSQCPPNLHKLDGYYCDHEQGRCYGGRCKTRDRQCQALWGHAAADRFCYEKLNVEGTERGNCGRKGSGWVQCSKQDVLCGFLLCVNISGAPRLGDLGGDISSVTFYHQGKELDCRGGHVQLADGSDLSYVEDGTACGPNMLCLDHRCLPASAFNFSTCPGSGERRICSHHGVCSNEGKCICQPDWTGKDCSIHNPLPTSPPTGETERYKGPSGTNIIIGSIAGAVLVAAIVLGGTGWGFKNIRRGRSGGA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
100	N-linked (GlcNAc...) asparagine			UniProt GlyGen
167	N-linked (GlcNAc...) asparagine			UniProt GlyGen
609	N-linked (GlcNAc...) asparagine		G86182NS	UniProt GlyGen
677	N-linked (GlcNAc...) asparagine		G68490OW	UniProt GlyGen
714		34418053	G49108TO	The O-GlcNAc Database