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Matrix metalloproteinase-17

Summary

UniProt ID: Q9ULZ9
Gene Symbol: MMP17 MT4MMP
Gene ID: 4326
Organism: Homo sapiens (human)

External Links

GlyGen: Q9ULZ9
PubChem: Q9ULZ9
The Human Metabolome Database: HMDBP07806
Re-Glyco: Q9ULZ9

Annotation

Keyword: Alternative splicing Calcium Cell membrane Cleavage on pair of basic residues Disulfide bond Extracellular matrix GPI-anchor Metal-binding Metalloprotease Proteomics identification Reference proteome Repeat Signal Zinc Zymogen

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
kidney development
proteolysis	TAS	PMID
proteolysis	IEA	GO_REF
extracellular matrix organization	IBA	GO_REF
collagen catabolic process	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

collagen catabolic process

collagen metabolic process [inference]

collagen catabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization

external encapsulating structure organization [inference]

extracellular matrix organization

multicellular organismal process [inference]

behavior [inference]

feeding behavior [inference]

drinking behavior

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

kidney development

Displaying **all 4** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
plasma membrane	IEA	GO_REF
extracellular matrix	IEA	GO_REF
side of membrane

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

external encapsulating structure [inference]

extracellular matrix

side of membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
metalloendopeptidase activity	TAS	PMID
metalloendopeptidase activity	IEA	GO_REF
enzyme activator activity	TAS	PMID
zinc ion binding	TAS	PMID
zinc ion binding	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity [inference]

metalloaminopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity [inference]

metalloaminopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity

molecular function activator activity [inference]

enzyme activator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MRRRAARGPGPPPPGPGLSRLPLPLLLLLALGTRGGCAAPAPAPRAEDLSLGVEWLSRFGYLPPADPTTGQLQTQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRESVSPTAQPEEPPLLPEPPDNRSSAPPRKDVPHRCSTHFDAVAQIRGEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPVSDFSLPPGGIDAAFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQSPLWRGVPSTLDDAMRWSDGASYFFRGQEYWKVLDGELEVAPGYPQSTARDWLVCGDSQADGSVAAGVDAAEGPRAPPGQHDQSRSEDGYEVCSCTSGASSPPGAPGPLVAATMLLLLPPLSPGALWTAAQALTL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
137	N-linked (GlcNAc...) asparagine			UniProt GlyGen
318	N-linked (GlcNAc...) asparagine	28531887		UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Activation of Matrix Metalloproteinases	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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External Links

Annotation

International Collaboration

Acknowledgements