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MIRAGE
Sodium/calcium exchanger 2

Summary
UniProt ID
Q9UPR5
Gene Symbol
SLC8A2 KIAA1087 NCX2
Gene ID
6543
Organism
Homo sapiens (human)
The Human Metabolome Database
HMDBP03171
Re-Glyco
Q9UPR5
Annotation
Keyword
Antiport Calcium transport Calmodulin-binding Cell membrane Cell projection Glycoprotein Metal-binding Phosphoprotein Proteomics identification Reference proteome Repeat Signal Sodium transport Synapse Transmembrane helix
Gene Ontology (GO)
Displaying entries 1 - 5 of 37 in total
GO Term Evidence Code Reference
response to ischemia
intracellular calcium ion homeostasis
intracellular calcium ion homeostasis
intracellular calcium ion homeostasis
cell communication
GO Hierarchy
Displaying entries 1 - 5 of 10 in total
GO Term Evidence Code Reference
calcium:sodium antiporter activity
calcium:sodium antiporter activity
calcium:sodium antiporter activity
calcium:sodium antiporter activity
calmodulin binding
GO Hierarchy
Gene Ontology information from UniProt.
Annotation information from UniProt.
Sequence
MAPLALVGVTLLLAAPPCSGAATPTPSLPPPPANDSDTSTGGCQGSYRCQPGVLLPVWEPDDPSLGDKAARAVVYFVAMVYMFLGVSIIADRFMAAIEVITSKEKEITITKANGETSVGTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFQAGELGPGTIVGSAAFNMFVVIAVCIYVIPAGESRKIKHLRVFFVTASWSIFAYVWLYLILAVFSPGVVQVWEALLTLVFFPVCVVFAWMADKRLLFYKYVYKRYRTDPRSGIIIGAEGDPPKSIELDGTFVGAEAPGELGGLGPGPAEARELDASRREVIQILKDLKQKHPDKDLEQLVGIANYYALLHQQKSRAFYRIQATRLMTGAGNVLRRHAADASRRAAPAEGAGEDEDDGASRIFFEPSLYHCLENCGSVLLSVTCQGGEGNSTFYVDYRTEDGSAKAGSDYEYSEGTLVFKPGETQKELRIGIIDDDIFEEDEHFFVRLLNLRVGDAQGMFEPDGGGRPKGRLVAPLLATVTILDDDHAGIFSFQDRLLHVSECMGTVDVRVVRSSGARGTVRLPYRTVDGTARGGGVHYEDACGELEFGDDETMKTLQVKIVDDEEYEKKDNFFIELGQPQWLKRGISALLLNQGDGDRKLTAEEEEARRIAEMGKPVLGENCRLEVIIEESYDFKNTVDKLIKKTNLALVIGTHSWREQFLEAITVSAGDEEEEEDGSREERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFGVSILVIGLLTALIGDLASHFGCTVGLKDSVNAVVFVALGTSIPDTFASKVAALQDQCADASIGNVTGSNAVNVFLGLGVAWSVAAVYWAVQGRPFEVRTGTLAFSVTLFTVFAFVGIAVLLYRRRPHIGGELGGPRGPKLATTALFLGLWLLYILFASLEAYCHIRGF
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
34
  • N-linked (GlcNAc...) asparagine
817
  • N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 3 entries
Pathway Name Organism
Ion homeostasis Homo sapiens
Reduction of cytosolic Ca++ levels Homo sapiens
Sodium/Calcium exchangers Homo sapiens
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026