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ATP-binding cassette sub-family B member 6

Summary

UniProt ID: Q9VF20
Gene Symbol: ABCB6 CG4225 DmCG4225 Dmel\CG4225 Dmel_CG4225 EP(3)3387 HMT-1 Hmt-1 hmt-1
Gene ID: 41925
Organism: Drosophila melanogaster (fruit fly)

External Links

The O-GlcNAc Database: Q9VF20
Re-Glyco: Q9VF20

Annotation

Keyword: ATP-binding Cell membrane Disulfide bond Endoplasmic reticulum Endosome Golgi apparatus Lysosome Mitochondrion outer membrane Proteomics identification Reference proteome Secreted Translocase Transmembrane helix Transport

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	Reference
heme transport	IBA	GO_REF
transmembrane transport	IEA	GO_REF
cellular detoxification of cadmium ion	IGI	PMID

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

cellular detoxification [inference]

cellular detoxification of metal ion [inference]

cellular detoxification of cadmium ion

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

iron ion transport [inference]

iron coordination entity transport [inference]

heme transport

transmembrane transport

nitrogen compound transport [inference]

heme transport

detoxification [inference]

detoxification of inorganic compound [inference]

detoxification of cadmium ion [inference]

cellular detoxification of cadmium ion

cellular detoxification of metal ion [inference]

cellular detoxification of cadmium ion

cellular detoxification [inference]

cellular detoxification of metal ion [inference]

cellular detoxification of cadmium ion

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
Golgi membrane	IEA	GO_REF
extracellular region	IEA	GO_REF
mitochondrial outer membrane	IEA	GO_REF
lysosomal membrane	IEA	GO_REF
vacuolar membrane	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

membrane [inference]

plasma membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

early endosome membrane

late endosome membrane [inference]

multivesicular body membrane

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

Golgi membrane

vacuolar membrane

lytic vacuole membrane [inference]

lysosomal membrane

endosome membrane [inference]

early endosome membrane

late endosome membrane [inference]

multivesicular body membrane

organelle outer membrane [inference]

mitochondrial outer membrane

Displaying **all 5** entries
GO Term	Evidence Code	Reference
ATP binding	IEA	GO_REF GO_REF
ABC-type heme transporter activity	IBA	GO_REF
ABC-type heme transporter activity	IEA	GO_REF
ATP hydrolysis activity	IEA	GO_REF
heme binding	IBA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

transmembrane transporter activity [inference]

heme transmembrane transporter activity [inference]

ABC-type heme transporter activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ABC-type transporter activity [inference]

ABC-type heme transporter activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

tetrapyrrole binding [inference]

heme binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ABC-type transporter activity [inference]

ABC-type heme transporter activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MLYCPPNVTLSEVWTQHGISHCFMDTVGPAVYGGFLLLFGSIQLLMYRKYATRITDPTQISKSRLFAMQLFLLLLLPVLALLRFLMNARIYPDSAVYGYMIFSTCVVCFSYPFSICLILKERYYQLPSMPTRGHGLVLLLFWTLAFINESLAFINLRHEDWWFHLKTNKDQIEMGLFVTRFLCSLLIFVLGLKAPGIMAPYNPHQRLDNDTANESQGNVQTGSAFRNGWRKLRTVFPYLWPKKNIALQIAVIVCIILLLAGRVIKLFLPIYRKKLVDSLTIAPIVFRWDFVLIYVALSFLQGGGTGSMGLFNNLRTFLWIRVQQYTTREIEIELFRHLHQLSLRWHLQRKTGEVLRVMDRGTDSINNLLNYIVFSIAPTILDLLVAVAYFVYAFNWWFGLIVFLTMFLYIASTIAITEWRTKYQRRMNLADNEQRARSVDSLLNFETVKYYGAEHYEVDCYREAILKYQKEEFLSMLTLNMLNTAQNIILCLGLLAGSLLCVYLVVHHQTLTVGDFVLFSTYLMELYMPLNWFGTYYRAIQKNFVDMENMFDLLKEEEEIVDAPGCSPLLTAGGGIEFSNVTFGYSPEKIVLRNVSFTVPAGKTVAIVGPSGAGKSTIMRLLFRFYDVQTGAILIDGQNIKLVQQQSLRKAIGVVPQDTVLFNNTIFYNIEYAKLGASDEAVYEAARAADIHERILGFPEKYETKVGERGLRLSGGEKQRVAIARTLLKAPIIVLLDEATSALDTHTERNIQAALARVCANRTTIIVAHRLSTIIHADEILVLQQGSIAERGRHEELVLREDGIYADMWQQQLKNLDAEQSGGSDNGDASAESGSEKRRAGGAGGPSGTGTGGAHFRAGHAHGGAR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites