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Enhancer of mRNA-decapping protein 4 homolog

Summary

UniProt ID: Q9VKK1
Gene Symbol: Ge-1 CG6181
Gene ID: 34541
Organism: Drosophila melanogaster (fruit fly)

External Links

GlyGen: Q9VKK1
PubChem: Q9VKK1
Re-Glyco: Q9VKK1

Annotation

Keyword: 3D-structure Coiled coil Cytoplasm Phosphoprotein Reference proteome Repeat WD repeat

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
deadenylation-dependent decapping of nuclear-transcribed mRNA	NAS	PMID
deadenylation-dependent decapping of nuclear-transcribed mRNA	IGI	PMID
mRNA catabolic process	IMP	PMID
deadenylation-independent decapping of nuclear-transcribed mRNA	IEA	GO_REF
P-body assembly	IMP	PMID PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

mRNA metabolic process [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

mRNA methylguanosine-cap decapping [inference]

RNA decapping [inference]

mRNA methylguanosine-cap decapping [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

mRNA metabolic process [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

mRNA methylguanosine-cap decapping [inference]

RNA decapping [inference]

mRNA methylguanosine-cap decapping [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle assembly [inference]

membraneless organelle assembly [inference]

P-body assembly

cellular component assembly [inference]

organelle assembly [inference]

membraneless organelle assembly [inference]

P-body assembly

localization [inference]

macromolecule localization [inference]

RNA localization [inference]

pole plasm RNA localization [inference]

pole plasm mRNA localization [inference]

pole plasm oskar mRNA localization

intracellular mRNA localization [inference]

intracellular mRNA localization involved in pattern specification process [inference]

intracellular mRNA localization involved in anterior/posterior axis specification [inference]

pole plasm mRNA localization [inference]

pole plasm oskar mRNA localization

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of gene expression [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of gene expression [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

Displaying **all 3** entries
GO Term	Evidence Code	Reference
P-body	IDA	PMID PMID PMID PMID PMID PMID
P-body	IEA	GO_REF GO_REF
pole plasm	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm [inference]

pole plasm

organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

P-body

intracellular organelle [inference]

intracellular membraneless organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

P-body

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

P-body

Displaying 1 entry
GO Term	Evidence Code	Reference
molecular condensate scaffold activity	IMP	PMID

GO Hierarchy

molecular function

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

molecular condensate scaffold activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MLIALFALAHLPIFRKTPLSASSSPPPSVHRSPRCGKASTAYHPPPADACISITASAIDAASGMSNSAEQDKPIAANGNAAEPQEIEVIHFQAQEKQCCRVIRSNKTKVLTSGGVHTRGSSKVKLKNIVDYKWERKYYYPGHLVAVHRDGKHLAYAINVNNKATGMEGMVRVCNIATSMRALIKGMSGEVLDLQFAHTDCERILAVIDVSSLFVYKVDQIEGNLLCNLVLKVEDPIANYVPEYDMVSWCPYVCSSSATVPINDDDDENQLLIWSRSSQFQCFQVKMIVSEHGRGKIQPAALESGYLKIEEDSLITCAALSPDGTTVAAACADGLVRFYQIYLFDVRNHRCLHEWKPHDGKKVCSLFFLDNINKPVEESYWQHVITTSDANTEIKLWNCSLWKCLQTINVVASPSSLQPRNFIAGIDRSANYLVLSCLDSLAVYVMQIGSTGGADSENRSSDSEGEGCDTSKRIQNVAEFKLSSGILSFSIVNASMRRVKNSIESYYPIEEPDDFDDDSNSTSALVLHMFVVQAKSLQECQIIYQPCVAEKTERSSLNSKRSQTPEDNLLIKEEPESPNSGTVGAVQLDALFAKSAKRASTGSSSAMVAVAAAAAAAPSAILQDATKEAAKSESPQLSSAYTQQVNLMTPDAFSASGTAAAAAVFVSTSTTTSIGTDSSTTTSGQDRSIDSAVLQTIRMLATVTSKTSENPNAEVLLNLMNNTLIEDREQQKLKEKLDARKKFIAIDRNPERNVAENLASGSSSPSREVQEIMATQDDADAYEAELENLDDDDDDEEEELANSSPLPEAVDGTWPIVKLSSHSAELQNAAQIMSQAVQNTNNGNVPPTLGGGHNNNTSVGSNSNNNTATTLSTSNTSSSNNAGGTCVDSSGTGELNAKMELLIDLVKAQSKQINKLENEVNKLQKQQEAAAALHSKQDTSLEPKNLSQLAYKIEMQLSKLMEQYLKRYENEHKKKLTEFLAARESQNRELRDSVLQVLNQYVMNHFTDIIGNVLNMELQRQLLPRVNANMDQLQAQMQVEIVQKLSVFDKTVKENIAQVCKSKQFLDTFGKSVLIGVQTSLQTAFIESMSSTLIPAYEKSSQNMFKQLHDAFSVGIKDFMVQFNTYLQHMPQPQAGSGNTEEINNKLSMLKQLVESSLHKHRTELTDAMLETQREVKSLEILLARQVQETIRAELRKHMEAQNVAMRSQAATPAPPYDLRDSIKQLLMAGQINKAFHQALLANDLGLVEFTLRHTDSNQAFAPEGCRLEQKVLLSLIQQISADMTNHNELKQRYLNEALLAINMADPITREHAPKVLTELYRNCQQFIKNSPKNSQFSNVRLLMKAIITYRDQLK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
1211				GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
mRNA decay by 5' to 3' exoribonuclease	Drosophila melanogaster

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

International Collaboration

Acknowledgements