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MIRAGE

ATP-dependent RNA helicase DDX42

Summary

UniProt ID: Q9VTC1
Gene Symbol: CG6418 DmRH27 Dmel\CG6418 Dmel_CG6418 cg6418
Gene ID: 39218
Organism: Drosophila melanogaster (fruit fly)

External Links

GlyGen: Q9VTC1
Re-Glyco: Q9VTC1

Annotation

Keyword: Coiled coil Cytoplasm Helicase Nucleus Proteomics identification Reference proteome

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	Reference
protein localization	ISS	GO_REF
intracellular protein localization	ISS	GO_REF
regulation of gene expression	IEA	GO_REF

GO Hierarchy

biological process

localization [inference]

macromolecule localization [inference]

intracellular protein localization

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

Displaying **all 2** entries
GO Term	Evidence Code	Reference
nucleus	IEA	GO_REF
cytoplasm	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 5** entries
GO Term	Evidence Code	Reference
RNA binding	ISS	GO_REF
RNA helicase activity	ISS	GO_REF
RNA helicase activity	IEA	GO_REF GO_REF
ATP binding	IEA	GO_REF GO_REF
hydrolase activity	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

isomerase activity [inference]

macromolecular conformation isomerase activity [inference]

nucleic acid conformation isomerase activity [inference]

helicase activity [inference]

RNA helicase activity

catalytic activity, acting on a nucleic acid [inference]

helicase activity [inference]

RNA helicase activity

catalytic activity, acting on RNA [inference]

RNA helicase activity

binding [inference]

nucleic acid binding [inference]

RNA binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

ATP-dependent activity [inference]

helicase activity [inference]

RNA helicase activity

ATP-dependent activity, acting on RNA [inference]

RNA helicase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSGYRGIGGGGFPYRKPASSGNNMNAVPPPPMLNARGYSGSRGGFGGASRGGVTGSTTSTSKHGYSTLDSISQYTNATNLVGKRKHHTDDDYFDDDDEPREKEIEQAYIPAPGSPGAPPTSAKKQEDSDSDEDPLEQFMAGINQQVEKEKRQQAPKPPTQAVRGDIDDEDDEESYYRYMKENPNAGLRDEGSDQEIEYDEDGNPIAPPKKKDIDPLPPIYHSEIEYEPFEKNFYTQHDDIAALDDEQVRELRRTLGVKVTGPSPPKPVTSFGHFGFDEQLIKAVRKAEYTQPTPIQAQAVPTALSGRDIIGIAKTGSGKTAAFIWPMLMHVMDQKQLKPGDGPIGLILAPTRELSLQIYNEAKKFGKVYNLNVVCCYGGGSKWEQSKALEQGAEIIVATPGRMIDMVKMKATNLRRVTFLVLDEADRMFHMGFEPQVRSICNHVRPDRQCLMFSATFKKRIERLARDVLSDPVRIVQGDLNEANQDITQSVYVFPNPLQKWNWLLCHLVKFLSEGSVLIFVTKKVDAETVSNNLLIKEYNCLLLHGDMDQADRNKVITQFKRKECDILVATDVAARGLDIPHIRNVVNYDTARDIETHTHRIGRTGRAGEKGNAYTLVTDKDKEFAGHLVRNLEGADQLVPDDLMELAMKSSWFRSSRFKQGKGKRPTNTHTGLGYREKGNGGGGYGSAGGSESTASVSAHSPSDGPSSKAFSSSGPATDRYTAMREAFRSQYNNQFRASSDRTWEKTLPESGVFAAPMAPPSSSTQGASASSANNSSNQDAKRAKKSRWN

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
120				GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
CHD1 and CHD2 subfamily	Drosophila melanogaster
U12 Dependent Splicing	Drosophila melanogaster
mRNA Polyadenylation	Drosophila melanogaster
pre-mRNA splicing	Drosophila melanogaster

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026