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Cytokine receptor

Summary

UniProt ID: Q9VWE0
Gene Symbol: CG14226 dome
Gene ID: 32976
Organism: Drosophila melanogaster (fruit fly)

External Links

PubChem: Q9VWE0
Re-Glyco: Q9VWE0

Annotation

Keyword: Cell membrane Developmental protein Disulfide bond Glycoprotein Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	Reference
compound eye morphogenesis	IMP	PMID
cell surface receptor signaling pathway via JAK-STAT	IDA	PMID PMID PMID PMID
cell surface receptor signaling pathway via JAK-STAT	IMP	PMID PMID PMID
cell surface receptor signaling pathway via JAK-STAT	IGI	PMID PMID PMID
border follicle cell migration	IMP	PMID PMID

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

cell surface receptor signaling pathway via STAT [inference]

cell surface receptor signaling pathway via JAK-STAT

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

epithelial cell migration [inference]

follicle cell of egg chamber migration [inference]

border follicle cell migration

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

memory [inference]

long-term memory

pattern specification process [inference]

regionalization [inference]

segmentation [inference]

blastoderm segmentation

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry [inference]

determination of digestive tract left/right asymmetry

embryonic pattern specification [inference]

blastoderm segmentation

behavior [inference]

learning or memory [inference]

memory [inference]

long-term memory

rhythmic behavior [inference]

circadian behavior [inference]

locomotor rhythm

locomotory behavior [inference]

locomotor rhythm

developmental process [inference]

anatomical structure morphogenesis [inference]

hindgut morphogenesis

animal organ morphogenesis [inference]

imaginal disc morphogenesis [inference]

wing disc morphogenesis

sensory organ morphogenesis [inference]

eye morphogenesis [inference]

compound eye morphogenesis

anatomical structure development [inference]

regeneration [inference]

tissue regeneration

system development [inference]

respiratory system development [inference]

open tracheal system development

growth [inference]

developmental growth [inference]

tissue regeneration

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

rhythmic process [inference]

circadian rhythm [inference]

circadian behavior [inference]

locomotor rhythm

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

cell surface receptor signaling pathway via STAT [inference]

cell surface receptor signaling pathway via JAK-STAT

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

Displaying **all 3** entries
GO Term	Evidence Code	Reference
plasma membrane	TAS	Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome
apical plasma membrane	IDA	PMID PMID
apicolateral plasma membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
cytokine receptor activity	IDA	PMID PMID
cytokine receptor activity	IGI	PMID PMID
protein heterodimerization activity	IPI	PMID PMID
STAT family protein binding	IPI	PMID
SOCS family protein binding	IPI	PMID

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

transcription factor binding [inference]

DNA-binding transcription factor binding [inference]

RNA polymerase II-specific DNA-binding transcription factor binding [inference]

STAT family protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein tyrosine kinase binding

protein dimerization activity [inference]

protein heterodimerization activity

SOCS family protein binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity

immune receptor activity [inference]

cytokine receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MVAQEQLVLLLMLLAGCRGGANAILDPGWVIPSKVEQLIGGDFNLSCTLNEDYFNGKSAEDCPVEKLYFTGGGRVYRDSKHIRILNNTTILFSDTNAVEQENDYHCMCDEYVINKSKVYVGTRPLLVRDFNCLDYDFQFMVCNFTQPPNTVITKYNISYNTNNDWRYSNTLDCNFDSAPVVTCNLTDDNYKRFSETFYFRLSISNALGHETQPITINHFERLVPARPGQNLTLLNRTESSVCLSWEMPRRSNYNRGLVWQVRVTPQNFEPITRPSWRNHTLTIKDTLCLTELPFAGYNYTLRVRVRANQNNTLWSEPMIYAFATAPAPPRRPPRVTYGSFYVYSSEKAMRFYWEPLEEHELNGPDFRYSISEYRINGTAVDPGLIKVESNSAMIDHWSMSAVHHFLIRSSNSQGLSVNATPMTIGPISNRDFKVREPRNIRSVYHPTNKSYTLSWDPPSDQRELQNYTVFWCVPKPGLQSECEGSIRFAEVASGLHHFTTSPDQLLTLHMAVSANYQSHNTGLHWAICSSDKKDDLAKMEPSIDVATSTSLTVSWSERVCAVILAGYNLTYCQRSAGRPDNCTTVTIDRYTNKHVIQNLVPYTDYSVKMLMYSDSRVSKYSDELVNRTGEAAPSQPRELQLIRVTSDSVELAWKPPLLANGVVRAYEGTFRSLHDNVTDTFRVSASADELVNNEKPITYRLGNLTAFTKYEISVRARTVYPSEPSNVILFSTAIGVPSPPQLYVINNPDQSSRLDWEPPRTPAGRIDFYEISLRDNNASCLTSTILPGRNLSYVMATPRCTSHNPFQLAVRAINVEQHPQLNGADAAEGAVLLMSTNGKGCEARTDALGEEERLQFEAYAANMTAYRLYRSDWGIYGFICTPDTHSVKAMYQTIEVTVAILVLGVIFYLVYKKYRKMSDIGLVLPQGIMETMKKPIDMGGLGLGLGPDSSVSGGIVCTRVDDSPPYTPQDLPHDFSSCGSESSKLLLRTASSSGGGGCVDRDGYDDNHETGPISAVGPPTSYLAMRHGLLVQNDRERERERDREQEREREQQQQQRESEMDREQSCTNGYIKPTQMKSWGGNGPSDNDHTFSVPSTAMTAPMSQPLSQIPLSGYVPVPIPQSRFNPAPVQPFGSPAVPSAATAAAASTFFPPAHLLNMDNYVQASDLHKLKPLVAAPLSQTGGPAFAGSSPATSPPLQLPPVHAASPAAATPKMADIGYTTMEQLQLTGLIKPPLAATVGSPTHAAGGAPGGGNQHSRLQPQINGYVTPQDLNAMAHNRHVL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 23 in total

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Position	Description	Source
44	N-linked (GlcNAc...) asparagine	UniProt
86	N-linked (GlcNAc...) asparagine	UniProt
87	N-linked (GlcNAc...) asparagine	UniProt
114	N-linked (GlcNAc...) asparagine	UniProt
143	N-linked (GlcNAc...) asparagine	UniProt
156	N-linked (GlcNAc...) asparagine	UniProt
184	N-linked (GlcNAc...) asparagine	UniProt
230	N-linked (GlcNAc...) asparagine	UniProt
235	N-linked (GlcNAc...) asparagine	UniProt
278	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Dephosphorylation by PTP61F phosphatases	Drosophila melanogaster
Formation of the activated STAT92E dimer and transport to the nucleus	Drosophila melanogaster
Formation of the activated receptor complex	Drosophila melanogaster
Neutrophil degranulation	Drosophila melanogaster

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:934	viral infectious disease	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements