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Membrane-bound transcription factor site-1 protease
Summary
- UniProt ID
- Q9WTZ3
- Gene Symbol
-
- Mbtps1
- S1p
- Ski1
- Organism
- Rattus norvegicus (Norway rat)
External Links
- PubChem
- Q9WTZ3
Annotation
- Keyword
-
- Autocatalytic cleavage
- Calcium
- Cholesterol metabolism
- Endoplasmic reticulum
- Glycoprotein
- Golgi apparatus
- Phosphoprotein
- Reference proteome
- Serine protease
- Signal
- Transmembrane helix
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| endoplasmic reticulum membrane |
| Golgi stack |
| Golgi membrane |
| Golgi apparatus |
| GO Term |
|---|
| serine-type endopeptidase activity |
Sequence
MKLVNIWLLLLVVLLCGKKHLGDRLGKKAFEKAPCPSCSHLTLKVEFSSTVVEYEYIVAFNGYFTAKARNSFISSALKSSEVDNWRIIPRNNPSSDYPSDFEVIQIKEKQKAGLLTLEDHPNIKRVTPQRKVFRSLKFAESDPIVPCNETRWSQKWQSSRPLKRASLSLGSGFWHATGRHSSRRLLRAIPRQVAQTLQADVLWQMGYTGANVRVAVFDTGLSEKHPHFKNVKERTNWTNERTLDDGLGHGTFVAGVIASMRECQGFAPDAELHIFRVFTNNQVSYTSWFLDAFNYAILKKIDVLNLSIGGPDFMDHPFVDKVWELTANNVIMVSAIGNDGPLYGTLNNPADQMDVIGVGGIDFEDNIARFSSRGMTTWELPGGYGRVKPDIVTYGAGVRGSGVKGGCRALSGTSVASPVVAGAVTLLVSTVQKRELVNPASVKQALIASARRLPGVNMFEQGHGKLDLLRAYQILSSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPEWRPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHIMITVASPAETELKNGAEHTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHVHTNFRDMYQHLRSMGYFVEVLGAPFTCFDATQYGTLLMVDSEEEYFPEEIAKLRRDVDNGLSLVVFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANVPALNELLSVWNMGFSDGLYEGEFALANHDMYYASGCSIARFPEDGVVITQTFKDQGLEVLKQETAVVDNVPILGLYQIPAEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGLAPPERMEGNHLHRYSKVLEAHLGDPKPRPLPACPHLSWAKPQPLNETAPSNLWKHQKLLSIDLDKVVLPNFRSNRPQVRPLSPGESGAWDIPGGIMPGRYNQEVGQTIPVFAFLGAMVALAFFVVQISKAKSRPKRRRPRAKRPQLAQQAHPARTPSV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 148 | N-linked (GlcNAc...) asparagine |
|
||
| 236 | N-linked (GlcNAc...) asparagine |
|
||
| 305 | N-linked (GlcNAc...) asparagine |
|
||
| 515 | N-linked (GlcNAc...) asparagine |
|
||
| 728 | N-linked (GlcNAc...) asparagine |
|
||
| 939 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ATF6 (ATF6-alpha) activates chaperones | Rattus norvegicus |
| ATF6B (ATF6-beta) activates chaperones | Rattus norvegicus |
| CREB3 factors activate genes | Rattus norvegicus |
| Post-translational protein phosphorylation | Rattus norvegicus |
| Regulation of IGF Activity by IGFBP | Rattus norvegicus |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | Rattus norvegicus |
