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Kunitz-type protease inhibitor 2

Summary

UniProt ID: Q9WU03
Gene Symbol: Hai2 Spint2
Gene ID: 20733
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0007780
Re-Glyco: Q9WU03

Annotation

Keyword: Alternative splicing Cell membrane Cytoplasm Disulfide bond Glycoprotein Reference proteome Repeat Serine protease inhibitor Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
neural tube closure	IMP	PMID
neural tube closure	IGI	PMID
establishment or maintenance of cell polarity	IMP	PMID
establishment or maintenance of cell polarity	IBA	GO_REF
negative regulation of cell-cell adhesion	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

establishment or maintenance of cell polarity

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization [inference]

basement membrane organization

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

basement membrane organization

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis [inference]

epithelial cell morphogenesis [inference]

epithelial cell morphogenesis involved in placental branching

embryonic morphogenesis [inference]

epithelial cell morphogenesis involved in placental branching

anatomical structure formation involved in morphogenesis [inference]

tube formation [inference]

tube closure [inference]

neural tube closure

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility

regulation of cell motility [inference]

negative regulation of cell motility

negative regulation of biological process [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion

negative regulation of cell population proliferation [inference]

negative regulation of neural precursor cell proliferation

negative regulation of cell motility

regulation of cellular process [inference]

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of neural precursor cell proliferation

regulation of neural precursor cell proliferation [inference]

negative regulation of neural precursor cell proliferation

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion

negative regulation of cell population proliferation [inference]

negative regulation of neural precursor cell proliferation

negative regulation of cell motility

regulation of cell motility [inference]

negative regulation of cell motility

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
cytoplasm	ISS	GO_REF
cytoplasm	ISO	GO_REF
cytoplasm	IEA	GO_REF GO_REF
Golgi apparatus	ISO	GO_REF
Golgi apparatus	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 3** entries
GO Term	Evidence Code	Reference
serine-type endopeptidase inhibitor activity	ISO	GO_REF
serine-type endopeptidase inhibitor activity	IBA	GO_REF
serine-type endopeptidase inhibitor activity	IEA	GO_REF GO_REF

GO Hierarchy

molecular function

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

peptidase regulator activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

endopeptidase regulator activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAQLCELRRGRALLALVASLLLSGAQVASRELDVHESCGVSKVVGKCRASIPRWWYNITDGSCQPFVYGGCEGNGNNYQSKEECLDKCAGVTENTTDDMARNRNGADSSVLSVPRKQSAEDLSAEIFNYEEYCVPKAVTGPCRAAFPRWYYDTEKNSCISFIYGGCRGNKNSYLSQEACMQHCSGKQMHPFLTPGLKAVILVGLFLMVLILLLGTSMVCLIRVVRRKQERALRTVWSTADDKEQLVKNTCVL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
57	N-linked (GlcNAc...) asparagine			UniProt
94	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
MET Receptor Activation	Mus musculus
Signaling by MST1	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements