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Glycogen synthase kinase-3 beta

Summary

UniProt ID

Q9WV60

Gene Symbol

Gsk3b

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q9WV60
PubChem: Q9WV60
The O-GlcNAc Database: Q9WV60
O-GlcNAcAtlas: Q9WV60

Annotation

Keyword

3D-structure
ADP-ribosylation
ATP-binding
Biological rhythms
Cell membrane
Cytoplasm
Developmental protein
Differentiation
Glycogen metabolism
Neurogenesis
Nucleus
Palmitate
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Signal transduction inhibitor
Wnt signaling pathway

Gene Ontology (GO)

Displaying entries **51 - 60** of **104** in total

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GO Term
maintenance of cell polarity
regulation of axon extension
negative regulation of TOR signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of neuronal synaptic plasticity
axon extension
phosphatidylinositol 3-kinase/protein kinase B signal transduction
positive regulation of axon extension
negative regulation of synaptic assembly at neuromuscular junction
positive regulation of synaptic assembly at neuromuscular junction

Displaying entries **21 - 24** of 24 in total

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GO Term
cytoplasm
microtubule
plasma membrane
membrane

Displaying entries **1 - 10** of 14 in total

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GO Term
protein kinase activity
protein serine/threonine kinase activity
kinase activity
beta-catenin binding
ionotropic glutamate receptor binding
protein serine kinase activity
protein serine/threonine kinase binding
protein kinase binding
tau-protein kinase activity
tau protein binding

Annotation information from UniProt.

Sequence

MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASPPANATAASDTNAGDRGQTNNAASASASNST

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	GlyTouCan ID	Source
9	G49108TO	GlyGen The O-GlcNAc Database
395	G49108TO	GlyGen
417	G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
B-WICH complex positively regulates rRNA expression	Mus musculus
Beta-catenin phosphorylation cascade	Mus musculus
CRMPs in Sema3A signaling	Mus musculus
Degradation of beta-catenin by the destruction complex	Mus musculus
Disassembly of the destruction complex and recruitment of AXIN to the membrane	Mus musculus
GLI3 is processed to GLI3R by the proteasome	Mus musculus
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	Mus musculus
Regulation of HSF1-mediated heat shock response	Mus musculus
Transcriptional and post-translational regulation of MITF-M expression and activity	Mus musculus