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2'-5'-oligoadenylate synthase 3

Summary

UniProt ID

Q9Y6K5

Gene Symbol

OAS3
P/OKcl.4

Gene ID

4940

Organism

Homo sapiens (human)

External Links

GlyGen: Q9Y6K5
PubChem: Q9Y6K5
The Human Metabolome Database: HMDBP08494
The O-GlcNAc Database: Q9Y6K5
O-GlcNAcAtlas: Q9Y6K5
Re-Glyco: Q9Y6K5

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Antiviral defense
Cytoplasm
Direct protein sequencing
Innate immunity
Magnesium
Metal-binding
Nucleotidyltransferase
Nucleus
Phosphoprotein
RNA-binding
Reference proteome
Repeat

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
plasma membrane
membrane
intracellular membrane-bounded organelle
nucleoplasm
cytosol
extracellular space
cytoplasm

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 17 in total

1

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GO Term
positive regulation of interferon-beta production
positive regulation of tumor necrosis factor production
RIG-I signaling pathway
negative regulation of type I interferon-mediated signaling pathway
nucleobase-containing compound metabolic process
response to virus
defense response to bacterium
innate immune response
defense response to virus
negative regulation of viral genome replication

Displaying **all 4** entries
GO Term
2'-5'-oligoadenylate synthetase activity
metal ion binding
double-stranded RNA binding
ATP binding

Annotation information from UniProt.

Sequence

MDLYSTPAAALDRFVARRLQPRKEFVEKARRALGALAAALRERGGRLGAAAPRVLKTVKGGSSGRGTALKGGCDSELVIFLDCFKSYVDQRARRAEILSEMRASLESWWQNPVPGLRLTFPEQSVPGALQFRLTSVDLEDWMDVSLVPAFNVLGQAGSGVKPKPQVYSTLLNSGCQGGEHAACFTELRRNFVNIRPAKLKNLILLVKHWYHQVCLQGLWKETLPPVYALELLTIFAWEQGCKKDAFSLAEGLRTVLGLIQQHQHLCVFWTVNYGFEDPAVGQFLQRQLKRPRPVILDPADPTWDLGNGAAWHWDLLAQEAASCYDHPCFLRGMGDPVQSWKGPGLPRAGCSGLGHPIQLDPNQKTPENSKSLNAVYPRAGSKPPSCPAPGPTGAASIVPSVPGMALDLSQIPTKELDRFIQDHLKPSPQFQEQVKKAIDIILRCLHENCVHKASRVSKGGSFGRGTDLRDGCDVELIIFLNCFTDYKDQGPRRAEILDEMRAQLESWWQDQVPSLSLQFPEQNVPEALQFQLVSTALKSWTDVSLLPAFDAVGQLSSGTKPNPQVYSRLLTSGCQEGEHKACFAELRRNFMNIRPVKLKNLILLVKHWYRQVAAQNKGKGPAPASLPPAYALELLTIFAWEQGCRQDCFNMAQGFRTVLGLVQQHQQLCVYWTVNYSTEDPAMRMHLLGQLRKPRPLVLDPADPTWNVGHGSWELLAQEAAALGMQACFLSRDGTSVQPWDVMPALLYQTPAGDLDKFISEFLQPNRQFLAQVNKAVDTICSFLKENCFRNSPIKVIKVVKGGSSAKGTALRGRSDADLVVFLSCFSQFTEQGNKRAEIISEIRAQLEACQQERQFEVKFEVSKWENPRVLSFSLTSQTMLDQSVDFDVLPAFDALGQLVSGSRPSSQVYVDLIHSYSNAGEYSTCFTELQRDFIISRPTKLKSLIRLVKHWYQQCTKISKGRGSLPPQHGLELLTVYAWEQGGKDSQFNMAEGFRTVLELVTQYRQLCIYWTINYNAKDKTVGDFLKQQLQKPRPIILDPADPTGNLGHNARWDLLAKEAAACTSALCCMGRNGIPIQPWPVKAAV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites