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MIRAGE

Prostaglandin D2 receptor 2

Summary

UniProt ID: Q9Z2J6
Gene Symbol: Ptgdr2 Crth2 Gpr44
Gene ID: 14764
Organism: Mus musculus (house mouse)

External Links

PubChem: Q9Z2J6
Re-Glyco: Q9Z2J6

Annotation

Keyword: Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Phosphoprotein Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	Reference
chemotaxis	ISS	PMID
chemotaxis	ISO	GO_REF
chemotaxis	IDA	PMID
chemotaxis	IEA	GO_REF
G protein-coupled receptor signaling pathway	ISS	PMID

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

neuropeptide signaling pathway

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

calcium-mediated signaling

locomotion [inference]

taxis [inference]

chemotaxis

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of G protein-coupled receptor signaling pathway

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of germ cell proliferation [inference]

negative regulation of male germ cell proliferation

negative regulation of multicellular organismal process [inference]

negative regulation of germ cell proliferation [inference]

negative regulation of male germ cell proliferation

negative regulation of reproductive process [inference]

negative regulation of male germ cell proliferation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of G protein-coupled receptor signaling pathway

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

neuropeptide signaling pathway

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

calcium-mediated signaling

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of G protein-coupled receptor signaling pathway

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of germ cell proliferation [inference]

negative regulation of male germ cell proliferation

regulation of germ cell proliferation [inference]

negative regulation of germ cell proliferation [inference]

negative regulation of male germ cell proliferation

regulation of male germ cell proliferation [inference]

negative regulation of male germ cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of germ cell proliferation [inference]

negative regulation of male germ cell proliferation

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of germ cell proliferation [inference]

negative regulation of male germ cell proliferation

regulation of germ cell proliferation [inference]

negative regulation of germ cell proliferation [inference]

negative regulation of male germ cell proliferation

regulation of male germ cell proliferation [inference]

negative regulation of male germ cell proliferation

regulation of reproductive process [inference]

negative regulation of reproductive process [inference]

negative regulation of male germ cell proliferation

Displaying **all 4** entries
GO Term	Evidence Code	Reference
plasma membrane	ISS	PMID
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF
neuron projection	IBA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
prostaglandin J receptor activity	IDA	PMID
G protein-coupled receptor activity	ISS	PMID
G protein-coupled receptor activity	ISO	GO_REF
G protein-coupled receptor activity	IDA	PMID
G protein-coupled receptor activity	IEA	GO_REF GO_REF

GO Hierarchy

molecular function

binding [inference]

peptide binding [inference]

neuropeptide binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

icosanoid receptor activity [inference]

prostanoid receptor activity [inference]

prostaglandin receptor activity [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MANVTLKPLCPLLEEMVQLPNHSNSSLRYIDHVSVLLHGLASLLGLVENGLILFVVGCRMRQTVVTTWVLHLALSDLLAAASLPFFTYFLAVGHSWELGTTFCKLHSSVFFLNMFASGFLLSAISLDRCLQVVRPVWAQNHRTVAVAHRVCLMLWALAVLNTIPYFVFRDTIPRLDGRIMCYYNLLLWNPGPDRDTTCDYRQKALAVSKFLLAFMVPLAIIASSHVAVSLRLHHRGRQRTGRFVRLVAAIVVAFVLCWGPYHIFSLLEARAHSVTTLRQLASRGLPFVTSLAFFNSVVNPLLYVFTCPDMLYKLRRSLRAVLESVLVEDSDQSGGLRNRRRRASSTATPASTLLLADRIPQLRPTRLIGWMRRGSAEVPQRV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
3	N-linked (GlcNAc...) asparagine			UniProt
21	N-linked (GlcNAc...) asparagine			UniProt
24	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
G alpha (i) signalling events	Mus musculus
Prostanoid ligand receptors	Mus musculus

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026