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Non-selective voltage-gated ion channel VDAC1

Summary

UniProt ID

Q9Z2L0

Gene Symbol

VDAC
Vdac1

Gene ID

83529

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: Q9Z2L0
PubChem: Q9Z2L0
The O-GlcNAc Database: Q9Z2L0
RaftProt: Q9Z2L0
O-GlcNAcAtlas: Q9Z2L0
Re-Glyco: Q9Z2L0

Annotation

Keyword

ATP-binding
Acetylation
Apoptosis
Cell membrane
Direct protein sequencing
Isopeptide bond
Lipid transport
Lipid-binding
Mitochondrion outer membrane
NAD
Phosphoprotein
Porin
Reference proteome
Transmembrane beta strand
Ubl conjugation

Gene Ontology (GO)

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GO Term
plasma membrane
membrane
mitochondrial membrane
protein-containing complex
mitochondrial nucleoid
mitochondrion
synaptic vesicle
membrane raft
presynaptic active zone membrane
postsynaptic density membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
lipid transport
apoptotic process
chemical synaptic transmission
epithelial cell differentiation
negative regulation of apoptotic process
calcium import into the mitochondrion
negative regulation of calcium import into the mitochondrion
regulation of mitophagy
negative regulation of reactive oxygen species metabolic process
positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

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GO Term
ceramide binding
monoatomic anion channel activity
calcium channel activity
ATP binding
voltage-gated monoatomic anion channel activity
porin activity
protein kinase binding
phosphatidylcholine binding
oxysterol binding
cholesterol binding

Annotation information from UniProt.

Sequence

MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites