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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
72 kDa type IV collagenase
Summary
- UniProt ID
- P33434
- Gene Symbol
-
- Mmp2
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003572
- PubChem
- P33434
Annotation
- Keyword
-
- Alternative splicing
- Angiogenesis
- Autocatalytic cleavage
- Calcium
- Collagen degradation
- Cytoplasm
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Membrane
- Metal-binding
- Metalloprotease
- Mitochondrion
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Zinc
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| angiogenesis |
| ovarian follicle development |
| luteinization |
| blood vessel maturation |
| intramembranous ossification |
| proteolysis |
| response to oxidative stress |
| tissue remodeling |
| extracellular matrix organization |
| collagen catabolic process |
| GO Term |
|---|
| extracellular space |
| nucleus |
| plasma membrane |
| sarcomere |
| extracellular matrix |
| mitochondrion |
| GO Term |
|---|
| peptidase activity |
| zinc ion binding |
| fibronectin binding |
| metalloendopeptidase activity |
Sequence
MEARVAWGALAGPLRVLCVLCCLLGRAIAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARALKVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGREYSSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNADGQPCKFPFRFQGTSYNSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRNDGKVWCATTTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSHDDIKGIQELYGPSPDADTDTGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPTGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWVYSASTLERGYPKPLTSLGLPPDVQQVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADSWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 303 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of Matrix Metalloproteinases | Mus musculus |
| Collagen degradation | Mus musculus |
| Degradation of the extracellular matrix | Mus musculus |
| EPH-ephrin mediated repulsion of cells | Mus musculus |
| Extra-nuclear estrogen signaling | Mus musculus |
