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MHC class I polypeptide-related sequence A
Summary
- UniProt ID
- Q29983
- Gene Symbol
-
- MICA
- PERB11.1
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011976
- GlyConnect
- GlyGen
- Q29983
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Alternative splicing
- Cell membrane
- Cytolysis
- Cytoplasm
- Disulfide bond
- Glycoprotein
- Host-virus interaction
- Immunoglobulin domain
- Palmitate
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| natural killer cell mediated cytotoxicity |
| defense response to bacterium |
| gamma-delta T cell activation |
| negative regulation of natural killer cell activation |
| negative regulation of natural killer cell mediated cytotoxicity |
| GO Term |
|---|
| external side of plasma membrane |
| cell surface |
| extracellular space |
| cytoplasm |
| plasma membrane |
| GO Term |
|---|
| natural killer cell lectin-like receptor binding |
| peptide antigen binding |
| signaling receptor binding |
Sequence
MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHWQTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHRDATQLGFQPLMSDLGSTGSTEGA
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:0060192 | Crohn's colitis | |
| DOID:0060262 | gallbladder disease | |
| DOID:0060643 | primary sclerosing cholangitis | |
| DOID:0060868 | leukoencephalopathy with vanishing white matter | |
| DOID:0080348 | Alzheimer's disease 1 | |
| DOID:0080409 | familial adenomatous polyposis 1 | |
| DOID:0090005 | Schwartz-Jampel syndrome 1 | |
| DOID:0110035 | Alzheimer's disease 2 | |
| DOID:0110037 | Alzheimer's disease 5 |
