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Receptor tyrosine-protein kinase erbB-4

Summary

UniProt ID

Q61527

Gene Symbol

Erbb4
Mer4

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0005494

GlyConnect

2677

GlyGen

Q61527

PubChem

Q61527

Annotation

Keyword

ATP-binding
Activator
Alternative splicing
Apoptosis
Cell membrane
Developmental protein
Disulfide bond
Glycoprotein
Lactation
Mitochondrion
Nucleus
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transcription regulation
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 45 in total

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GO Term
receptor signaling pathway via JAK-STAT
positive regulation of epithelial cell proliferation
negative regulation of muscle cell apoptotic process
central nervous system morphogenesis
olfactory bulb interneuron differentiation
neurogenesis
positive regulation of synaptic transmission, GABAergic
negative regulation of apoptotic process
cell fate commitment
positive regulation of cardiac muscle cell proliferation

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GO Term
basal plasma membrane
presynaptic membrane
postsynaptic density membrane
nucleus
plasma membrane
neuromuscular junction
postsynaptic membrane
dendrite
neuronal cell body
receptor complex

Displaying **all 9** entries
GO Term
GABA receptor binding
protein homodimerization activity
transcription cis-regulatory region binding
epidermal growth factor receptor activity
epidermal growth factor receptor binding
ATP binding
transmembrane receptor protein tyrosine kinase activity
neuregulin receptor activity
neuregulin binding

Annotation information from UniProt.

Sequence

MKLATGLWVWGSLLMAAGTVQPSASQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNMTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIDAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRRAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGKICIESCNLYDGEFREFENGSICVECDSQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADQDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLFILVIMALTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRSEIGHSPPPAYTPMSGNQFVYQDGGFATQQGMPMPYRATTSTIPEAPVAQGATAEMFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERNPRGELDEEGYMTPMHDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHSASSGPPKAEDEYVNEPLYLNTFANALGSAEYMKNSVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTMLPPPPYRHRNTVV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
174		17406563 22823882
181		17406563 22823882
576

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Mus musculus
RAF/MAP kinase cascade	Mus musculus
SHC1 events in ERBB2 signaling	Mus musculus
SHC1 events in ERBB4 signaling	Mus musculus
Signaling by ERBB2	Mus musculus
Signaling by ERBB4	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements