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Glycan Structure Repository
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Glycoconjugate Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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MCAW
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Guidelines
MIRAGE
Agglutinin isolectin 3 (Fragment)
Summary
- Lectin Name Aliases
-
- WGA
- Monosaccharide Specificities
-
- GlcNAc
- Organism
- Triticum aestivum (bread wheat)
Annotation
- Keyword
-
- 3D-structure
- Chitin-binding
- Disulfide bond
- Glycoprotein
- Lectin
- Pyrrolidone carboxylic acid
- Reference proteome
- Repeat
- Gene Ontology (GO)
| GO Term |
|---|
| chitin binding |
| carbohydrate binding |
Reference
| PubMed ID | Title | First Author |
|---|---|---|
| 163229 | Membrane receptors as general markers for plasma membrane isolation procedures. The use of 125-I-labeled wheat germ agglutinin, insulin, and cholera toxin. | Chang KJ |
| 1321144 | Crystal structure of a wheat germ agglutinin/glycophorin-sialoglycopeptide receptor complex. Structural basis for cooperative lectin-cell binding. | Wright CS |
| 2026615 | Purification of dystrophin from skeletal muscle. | Ervasti JM |
| 6315720 | Modification of nerve growth factor receptor properties by wheat germ agglutinin. | Grob PM |
| 6300053 | Change in state of nerve growth factor receptor. Modulation of receptor affinity by wheat germ agglutinin. | Buxser SE |
| 8286857 | Lectin-induced apoptosis of tumour cells. | Kim M |
| 8381403 | Structural and functional analysis of the human vasoactive intestinal peptide receptor glycosylation. Alteration of receptor function by wheat germ agglutinin. | Chochola J |
| 8608268 | A high degree of sequence homology in the putative carbohydrate recognition domains of pokeweed mitogen and wheat germ agglutinin: poly-N-acetyllactosamine-binding lectins from different species. | Konami Y |
| 9592123 | NMR investigations of protein-carbohydrate interactions: refined three-dimensional structure of the complex between hevein and methyl beta-chitobioside. | Asensio JL |
| 9719680 | Characterization of SPACR, a sialoprotein associated with cones and rods present in the interphotoreceptor matrix of the human retina: immunological and lectin binding analysis. | Acharya S |
Lectin Frontier DataBase (LfDB)
LfDB provides quantitative interaction data in terms of the affinity constants (Ka) of a series of lectins toward a panel of pyridylaminated (PA) glycans obtained by an automated frontal affinity chromatography with fluorescence detection (FAC-FD) system. Since the data are accurate and reliable, providing the absolute values of sugar-protein interactions, LfDB would be a valuable resource in the studies of glycan-related biology.
The MCAW profile of the top three glycans above, which resulted from FAC analysis.
The MCAW profile of the top three glycans above, which resulted from FAC analysis.
UniLectin
| UniProt |
|---|
| P10969 |
