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Aggrecan core protein

Summary

GlyCosmos Lectin

GL_000051

Lectin Name Aliases

CSPCP
Cartilage-specific proteoglycan core protein
Chondroitin sulfate proteoglycan 1
Chondroitin sulfate proteoglycan core protein 1

Organism

Homo sapiens (human)

External Links

UniProt: P16112
UniLectin: P16112

Annotation

Keyword: 3D-structure Alternative splicing Calcium Direct protein sequencing Disease variant Disulfide bond Dwarfism EGF-like domain Extracellular matrix Immunoglobulin domain Lectin Metal-binding Proteoglycan Proteomics identification Reference proteome Repeat Signal Sushi

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	Reference
skeletal system development	NAS	PMID
skeletal system development	IBA	GO_REF
proteolysis	NAS	PMID
cell adhesion	IEA	GO_REF
central nervous system development	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

developmental process [inference]

anatomical structure development [inference]

system development [inference]

animal gross anatomical part developmental process [inference]

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
extracellular region	TAS	Reactome Reactome Reactome Reactome Reactome Reactome
obsolete extracellular space
Golgi lumen	TAS	Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome Reactome
Golgi lumen	IEA	GO_REF
extracellular matrix	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

cell junction [inference]

synapse

external encapsulating structure [inference]

extracellular matrix

specialized extracellular matrix [inference]

synapse-associated extracellular matrix [inference]

perisynaptic extracellular matrix [inference]

perineuronal net

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

Golgi lumen

Displaying **all 4** entries
GO Term	Evidence Code	Reference
extracellular matrix structural constituent	TAS	PMID
hyaluronic acid binding	IEA	GO_REF
carbohydrate binding
metal ion binding

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent

binding [inference]

carbohydrate binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

hyaluronic acid binding

cation binding [inference]

metal ion binding

organic acid binding [inference]

carboxylic acid binding [inference]

hyaluronic acid binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Pathway

Displaying **all 7** entries
Pathway Name	Organism
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)	Homo sapiens
Defective CHST6 causes MCDC1	Homo sapiens
Defective ST3GAL3 causes MCT12 and EIEE15	Homo sapiens
Degradation of the extracellular matrix	Homo sapiens
ECM proteoglycans	Homo sapiens
Keratan sulfate biosynthesis	Homo sapiens
Keratan sulfate degradation	Homo sapiens