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C-type lectin domain family 12 member A

Summary

GlyCosmos Lectin

GL_000143

Lectin Name Aliases

C-type lectin-like molecule 1
CLL-1
DCAL-2
Dendritic cell-associated lectin 2
Killer cell C-type lectin-like receptor L1
MICL
Myeloid inhibitory C-type lectin-like receptor
hKLRL1

Organism

Homo sapiens (human)

External Links

UniProt: Q5QGZ9

Annotation

Keyword: 3D-structure Alternative splicing Cell membrane Disulfide bond Glycoprotein Lectin Phosphoprotein Proteomics identification Receptor Reference proteome Signal-anchor Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
signal transduction	IBA	GO_REF
positive regulation of type I interferon production	ISS	GO_REF
negative regulation of natural killer cell activation	IMP	PMID PMID
negative regulation of natural killer cell activation	IEA	GO_REF
negative regulation of inflammatory response	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

negative regulation of neutrophil activation

negative regulation of immune response

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

negative regulation of neutrophil activation

regulation of lymphocyte activation [inference]

regulation of natural killer cell activation [inference]

negative regulation of natural killer cell activation

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

regulation of neutrophil activation [inference]

negative regulation of neutrophil activation

regulation of immune response [inference]

negative regulation of immune response

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

regulation of dendritic cell differentiation [inference]

negative regulation of dendritic cell differentiation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

negative regulation of neutrophil activation

negative regulation of immune response

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

negative regulation of neutrophil activation

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

negative regulation of immune response

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

negative regulation of neutrophil activation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

negative regulation of immune response

regulation of immune response [inference]

negative regulation of immune response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

regulation of dendritic cell differentiation [inference]

negative regulation of dendritic cell differentiation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

regulation of dendritic cell differentiation [inference]

negative regulation of dendritic cell differentiation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

regulation of cellular process [inference]

signal transduction

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

regulation of type I interferon production [inference]

positive regulation of type I interferon production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

regulation of type I interferon production [inference]

positive regulation of type I interferon production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

regulation of dendritic cell differentiation [inference]

negative regulation of dendritic cell differentiation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

negative regulation of neutrophil activation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

negative regulation of neutrophil activation

regulation of lymphocyte activation [inference]

regulation of natural killer cell activation [inference]

negative regulation of natural killer cell activation

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

regulation of neutrophil activation [inference]

negative regulation of neutrophil activation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

negative regulation of neutrophil activation

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

regulation of type I interferon production [inference]

positive regulation of type I interferon production

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

negative regulation of neutrophil activation

regulation of lymphocyte activation [inference]

regulation of natural killer cell activation [inference]

negative regulation of natural killer cell activation

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

regulation of neutrophil activation [inference]

negative regulation of neutrophil activation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

negative regulation of neutrophil activation

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

negative regulation of neutrophil activation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

regulation of dendritic cell differentiation [inference]

negative regulation of dendritic cell differentiation

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of dendritic cell differentiation

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GO Term	Evidence Code	Reference
plasma membrane	EXP	PMID PMID
plasma membrane	TAS	Reactome Reactome
plasma membrane	IDA	PMID PMID PMID PMID PMID
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane [inference]

bounding membrane of organelle [inference]

secretory granule membrane [inference]

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
transmembrane signaling receptor activity	IDA	PMID PMID PMID
transmembrane signaling receptor activity	IMP	PMID
transmembrane signaling receptor activity	IBA	GO_REF
transmembrane signaling receptor activity	IEA	GO_REF
carbohydrate binding