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Galectin-9
Summary
- GlyCosmos Lectin
- GL_000514
- Lectin Name Aliases
-
- Ecalectin
- Gal-9
- Galectin-9
- Tumor antigen HOM-HD-21
- Organism
- Homo sapiens (human)
Annotation
- Keyword
- 3D-structure Alternative splicing Chemotaxis Cytoplasm Immunity Lectin Nucleus Proteomics identification Reference proteome Repeat Secreted
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| natural killer cell tolerance induction | ||
| negative regulation of T-helper 1 type immune response | ||
| chemotaxis |
|
|
| inflammatory response | ||
| female pregnancy |
GO Hierarchy
- positive regulation of activated T cell autonomous cell death
- positive regulation of activated T cell autonomous cell death
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-13 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of transforming growth factor beta production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-13 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of transforming growth factor beta production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-13 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of transforming growth factor beta production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-13 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of transforming growth factor beta production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-13 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of transforming growth factor beta production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-13 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of transforming growth factor beta production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-13 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of transforming growth factor beta production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-13 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of transforming growth factor beta production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-13 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of transforming growth factor beta production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-13 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of transforming growth factor beta production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-13 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of transforming growth factor beta production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-13 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of transforming growth factor beta production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-13 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of transforming growth factor beta production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-13 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of transforming growth factor beta production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-13 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of transforming growth factor beta production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-13 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of transforming growth factor beta production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-13 production
- positive regulation of interleukin-4 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of transforming growth factor beta production
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
negative regulation of immune system process [inference]
positive regulation of immune system process [inference]
positive regulation of leukocyte activation [inference]
regulation of leukocyte migration [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte proliferation [inference]
regulation of T cell activation [inference]
regulation of T cell proliferation [inference]
regulation of alpha-beta T cell activation [inference]
negative regulation of T cell activation [inference]
positive regulation of T cell activation [inference]
negative regulation of lymphocyte activation [inference]
positive regulation of lymphocyte activation [inference]
regulation of immune effector process [inference]
regulation of immune response [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of leukocyte activation [inference]
positive regulation of locomotion [inference]
positive regulation of cellular process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cell adhesion [inference]
positive regulation of cell-cell adhesion [inference]
positive regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
positive regulation of cell activation [inference]
negative regulation of biological process [inference]
negative regulation of immune system process [inference]
negative regulation of cellular process [inference]
negative regulation of multicellular organismal process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cell adhesion [inference]
negative regulation of cell adhesion [inference]
regulation of cell-cell adhesion [inference]
negative regulation of cell-cell adhesion [inference]
positive regulation of cell-cell adhesion [inference]
regulation of leukocyte cell-cell adhesion [inference]
negative regulation of leukocyte cell-cell adhesion [inference]
positive regulation of leukocyte cell-cell adhesion [inference]
positive regulation of cell adhesion [inference]
positive regulation of cell-cell adhesion [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cell adhesion [inference]
positive regulation of cell-cell adhesion [inference]
positive regulation of cell activation [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte proliferation [inference]
regulation of T cell activation [inference]
regulation of T cell proliferation [inference]
regulation of alpha-beta T cell activation [inference]
negative regulation of T cell activation [inference]
positive regulation of T cell activation [inference]
negative regulation of lymphocyte activation [inference]
positive regulation of lymphocyte activation [inference]
negative regulation of cell activation [inference]
positive regulation of cell activation [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte proliferation [inference]
regulation of T cell activation [inference]
regulation of T cell proliferation [inference]
regulation of alpha-beta T cell activation [inference]
negative regulation of T cell activation [inference]
positive regulation of T cell activation [inference]
negative regulation of lymphocyte activation [inference]
positive regulation of lymphocyte activation [inference]
negative regulation of cell activation [inference]
positive regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
positive regulation of cell activation [inference]
negative regulation of multicellular organismal process [inference]
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| galactose binding | ||
| galactoside binding | ||
| enzyme binding | ||
| carbohydrate binding | ||
| carbohydrate binding |
GO Hierarchy
Reference
| PubMed ID | Title | First Author |
|---|---|---|
| 9038233 | Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin. | Wada J |
| 16990264 | Crystal structure of the galectin-9 N-terminal carbohydrate recognition domain from Mus musculus reveals the basic mechanism of carbohydrate recognition. | Nagae M |
| 18977853 | Structural analysis of the recognition mechanism of poly-N-acetyllactosamine by the human galectin-9 N-terminal carbohydrate recognition domain. | Nagae M |
| 19776007 | Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation. | Niki T |
| 20861009 | X-ray structures of human galectin-9 C-terminal domain in complexes with a biantennary oligosaccharide and sialyllactose. | Yoshida H |
| 23836896 | Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis. | Steelman AJ |
| 25947381 | Impact of Exogenous Galectin-9 on Human T Cells: CONTRIBUTION OF THE T CELL RECEPTOR COMPLEX TO ANTIGEN-INDEPENDENT ACTIVATION BUT NOT TO APOPTOSIS INDUCTION. | Lhuillier C |
| 26582205 | Cooperative Interactions of Oligosaccharide and Peptide Moieties of a Glycopeptide Derived from IgE with Galectin-9. | Nakakita S |
| 28810662 | Galectin-9 binds to O-glycans on protein disulfide isomerase. | Schaefer K |
| 21187321 | Galectin-9 regulates T helper cell function independently of Tim-3. | Su EW |
Pathway
| Pathway Name | Organism |
|---|---|
| Interleukin-2 family signaling | Homo sapiens |
UniLectin
| UniProt |
|---|
| O00182 |
CarboGrove
- Lectin Name
- Human Galectin 9
- Common Name
- Gal 9
- Automated Analysis report (Top 10 high affinity glycans)
- Array Source
- GHMO
- Protein Source
- Investigator Provided
- Concentration (ug/mL)
-
G18059CR
G87373RB
G94393CX
G48059CD
G90411BS
G63110FF
G85278ER
G79420BT
G61710AG
G30622WV
G96548CQ
G72506RN
