GlyCosmos Portal

Submissions

Complement C4-B [Cleaved into: Complement C4 beta chain; Complement C4 alpha chain; C4a anaphylatoxin; Complement C4b-B; Complement C4 gamma chain]

Summary

GlyCosmos Lectin: GL_001412
Organism: Mus musculus (house mouse)

External Links

UniProt: P01029

Annotation

Keyword: Cleavage on pair of basic residues Complement pathway Disulfide bond Glycoprotein Inflammatory response Phosphoprotein Reference proteome Secreted Signal Sulfation Thioester bond

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	Reference
complement activation, lectin pathway	ISS	GO_REF
inflammatory response	IEA	GO_REF
complement activation	ISS	GO_REF
complement activation	IMP	PMID
complement activation	IBA	GO_REF

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte mediated immunity [inference]

lymphocyte mediated immunity [inference]

B cell mediated immunity [inference]

immunoglobulin mediated immune response

complement activation

activation of immune response [inference]

complement activation

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

B cell mediated immunity [inference]

immunoglobulin mediated immune response

humoral immune response [inference]

complement activation

innate immune response [inference]

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

B cell mediated immunity [inference]

immunoglobulin mediated immune response

humoral immune response [inference]

complement activation

innate immune response [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

regulation of immune response [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

regulation of immune response [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

Displaying entries **1 - 5** of 16 in total

1

2

3

4

Next ›

Last »
GO Term	Evidence Code	Reference
extracellular region	ISS	GO_REF
extracellular region	ISO	GO_REF GO_REF
extracellular region	IDA	PMID
extracellular region	IEA	GO_REF GO_REF
extracellular region	HDA	PMID

GO Hierarchy

cellular component

protein-containing complex [inference]

extracellular protein-containing complex [inference]

classical-complement-pathway C3/C5 convertase complex

catalytic complex [inference]

classical-complement-pathway C3/C5 convertase complex

cellular anatomical structure [inference]

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

other organism part [inference]

symbiont cell surface

cell body [inference]

neuronal cell body

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	Reference
complement binding	ISO	GO_REF
complement component C1q complex binding	ISO	GO_REF
antigen binding	ISS	GO_REF
antigen binding	ISO	GO_REF
endopeptidase inhibitor activity	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

antigen binding

protein binding [inference]

opsonin binding [inference]

complement component C1q complex binding

complement binding

complement component C1q complex binding

carbohydrate binding

protein-containing complex binding [inference]

complement component C1q complex binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity

peptidase regulator activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity

endopeptidase regulator activity [inference]

endopeptidase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Activation of C3 and C5	Mus musculus
Initial triggering of complement	Mus musculus
Post-translational protein phosphorylation	Mus musculus
Regulation of Complement cascade	Mus musculus
Regulation of IGF Activity by IGFBP	Mus musculus