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Keratin, type II cytoskeletal 1

Summary

GlyCosmos Lectin

GL_001670

Lectin Name Aliases

67 kDa cytokeratin
CK-1
Cytokeratin-1
K1
Keratin-1
Type-II keratin Kb1

Organism

Mus musculus (house mouse)

External Links

UniProt: P04104

Annotation

Keyword: Cell membrane Citrullination Coiled coil Cytoplasm Direct protein sequencing Disease variant Intermediate filament Keratin Methylation Phosphoprotein Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
complement activation, lectin pathway	ISO	GO_REF
complement activation, lectin pathway	IEA	GO_REF
keratinization	IBA	GO_REF
intermediate filament organization	IBA	GO_REF
negative regulation of inflammatory response	IMP	PMID

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

complement activation [inference]

complement activation, lectin pathway

activation of immune response [inference]

complement activation [inference]

complement activation, lectin pathway

immune response [inference]

humoral immune response [inference]

complement activation [inference]

complement activation, lectin pathway

innate immune response [inference]

complement activation, lectin pathway

cellular process [inference]

intermediate filament-based process [inference]

intermediate filament cytoskeleton organization [inference]

intermediate filament organization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

intermediate filament cytoskeleton organization [inference]

intermediate filament organization

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein tetramerization [inference]

protein heterotetramerization

protein heterooligomerization [inference]

protein heterotetramerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein tetramerization [inference]

protein heterotetramerization

protein heterooligomerization [inference]

protein heterotetramerization

supramolecular fiber organization [inference]

intermediate filament organization

multicellular organismal process [inference]

keratinization

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

epidermis development [inference]

skin epidermis development [inference]

establishment of skin barrier

epithelium development [inference]

skin epidermis development [inference]

establishment of skin barrier

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

complement activation, lectin pathway

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

complement activation, lectin pathway

immune response [inference]

humoral immune response [inference]

complement activation [inference]

complement activation, lectin pathway

innate immune response [inference]

complement activation, lectin pathway

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

complement activation, lectin pathway

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response [inference]

complement activation, lectin pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

complement activation, lectin pathway

regulation of immune response [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

complement activation, lectin pathway

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

complement activation, lectin pathway

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

complement activation, lectin pathway

negative regulation of biological process [inference]

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

complement activation, lectin pathway

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of immune response [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

complement activation, lectin pathway

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	Reference
cornified envelope	ISO	GO_REF
cornified envelope	IDA	PMID
cornified envelope	IEA	GO_REF
cytoplasm	ISS	GO_REF
cytoplasm	ISO	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

membrane

plasma membrane [inference]

cornified envelope

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

intermediate filament [inference]

keratin filament

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
carbohydrate binding	ISO	GO_REF
carbohydrate binding	IEA	GO_REF
structural constituent of skin epidermis	ISO	GO_REF
structural constituent of skin epidermis	IBA	GO_REF
structural constituent of skin epidermis	IEA	GO_REF

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of skin epidermis

binding [inference]

protein binding [inference]

protein dimerization activity [inference]

protein heterodimerization activity

carbohydrate binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Pathway

Displaying **all 5** entries
Pathway Name	Organism
FXIIa activates plasma kallikrein-kinin system	Mus musculus
Formation of the cornified envelope	Mus musculus
Keratinization	Mus musculus
Neutrophil degranulation	Mus musculus
Regulation of FXIIa and plasma kallikrein activity	Mus musculus