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Guidelines

MIRAGE

Lysosomal alpha-mannosidase

Summary

GlyCosmos Lectin

GL_004578

Lectin Name Aliases

Laman
Lysosomal acid alpha-mannosidase
Mannosidase alpha class 2B member 1
Mannosidase alpha-B

Organism

Mus musculus (house mouse)

External Links

UniProt: O09159

Annotation

Keyword: Disulfide bond Glycoprotein Glycosidase Lysosome Metal-binding Reference proteome Secreted Signal Zinc

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
mannose metabolic process	IDA	PMID PMID
mannose metabolic process	IMP	PMID
mannose metabolic process	IEA	GO_REF
learning or memory	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

mannose metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

mannose metabolic process

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory

behavior [inference]

learning or memory

Displaying entries **1 - 5** of 6 in total

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2

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GO Term	Evidence Code	Reference
obsolete extracellular space
nucleoplasm	ISO	GO_REF
lysosome	IBA	GO_REF
lysosomal lumen	ISS	GO_REF
lysosomal lumen	ISO	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

nucleoplasm

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
alpha-mannosidase activity	ISS	GO_REF
alpha-mannosidase activity	ISO	GO_REF GO_REF
alpha-mannosidase activity	IDA	PMID PMID
alpha-mannosidase activity	IMP	PMID
alpha-mannosidase activity	IEA	GO_REF GO_REF GO_REF GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

mannosidase activity [inference]

alpha-mannosidase activity

binding [inference]

carbohydrate binding [inference]

monosaccharide binding [inference]

D-mannose binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

monosaccharide binding [inference]

D-mannose binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Lysosomal oligosaccharide catabolism	Mus musculus
Neutrophil degranulation	Mus musculus

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026