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Release of apoptotic factors from the mitochondria

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-111457

PubChem

R-HSA-111457

Description

Apoptotic factors released from the mitochondria promote apoptosis through several different mechanisms. Cytochrome C participates in Apoptosome driven effector caspase activation while SMAC relieves IAP mediated caspase inhibition.

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 2** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P57764	Gasdermin-D	DFNA5L FKSG10 GSDMD GSDMDC1	view
Q07812	Apoptosis regulator BAX	BAX BCL2L4	view

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