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ATP sensitive Potassium channels

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-1296025

PubChem

R-HSA-1296025

Description

ATP sensitive K+ channels couple intracellular metabolism with membrane excitability. These channels are inhibited by ATP so are open in low metabolic states and close in high metabolic states, resulting in membrane depolarization triggering responses such as insulin secretion, modulation of vascular smooth muscle and cardioprotection. The channel comprises four Kir6.x subunits and four regulatory sulphonylurea receptors (SUR) (Akrouh et al, 2009).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 2** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O60706	ATP-binding cassette sub-family C member 9	ABCC9 SUR2	view
Q09428	ATP-binding cassette sub-family C member 8	ABCC8 HRINS SUR SUR1	view

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