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Activation of G protein gated Potassium channels

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-1296041

PubChem

R-HSA-1296041

Description

Activation of Kir 3 channels occurs after binding of G beta gamma subunits of GPCR. Activation of Kir3/GIRK leads to K+ efflux. The dissociation of GPCR into G alpha and G beta gamma subunits is activated by the activation of GABA B receptor by GABA binding.

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 6** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O75899	Gamma-aminobutyric acid type B receptor subunit 2	GABBR2 GPR51 GPRC3B	view
P48544	G protein-activated inward rectifier potassium channel 4	GIRK4 KCNJ5	view
P48549	G protein-activated inward rectifier potassium channel 1	GIRK1 KCNJ3	view
P62873	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	GNB1	view
Q9HAV0	Guanine nucleotide-binding protein subunit beta-4	GNB4	view
Q9UBS5	Gamma-aminobutyric acid type B receptor subunit 1	GABBR1 GPRC3A	view

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