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Voltage gated Potassium channels

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-1296072

PubChem

R-HSA-1296072

Description

Voltage-gated K+ channels (Kv) determine the excitability of heart, brain and skeletal muscle cells. Kv form octameric channel with alpha subunits that forms the pore of the channel and associated beta subunits. The alpha subunits associate with beta subunits with a stoichiometry of alpha4beta4.The alpha subunits have been classified into 12 families, 1-12 with several representatives from each family. Members of Kv 1-4 form both homotetramers and heterotetramers, however, members of Kv 5-12 form functional heterotetramers. Kv's are expressed in the axon, at axon nodes, somatodendritic sites and axon termini.

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 28 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O43525	Potassium voltage-gated channel subfamily KQT member 3	KCNQ3	view
O43526	Potassium voltage-gated channel subfamily KQT member 2	KCNQ2	view
O95259	Voltage-gated delayed rectifier potassium channel KCNH1	EAG EAG1 KCNH1	view
P16389	Potassium voltage-gated channel subfamily A member 2	KCNA2	view
P22001	Potassium voltage-gated channel subfamily A member 3	HGK5 KCNA3	view
P22459	Potassium voltage-gated channel subfamily A member 4	KCNA4 KCNA4L	view
P48547	Voltage-gated potassium channel KCNC1	KCNC1	view
P51787	Potassium voltage-gated channel subfamily KQT member 1	KCNA8 KCNA9 KCNQ1 KVLQT1	view
Q03721	Voltage-gated potassium channel KCNC4	C1orf30 KCNC4	view
Q09470	Potassium voltage-gated channel subfamily A member 1	KCNA1	view

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