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Acyl chain remodeling of CL

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-1482798

PubChem

R-HSA-1482798

Description

Acyl chain remodeling of cardiolipin (CL) occurs in the inner mitochondria membranes (IM) via hydrolysis by phopholipases and subsequent reacylation by acyltransferases. At the endoplasmic reticulum (ER) membrane the situation is more complicated with monolysocardiolipin (MLCL) involved in hydrolysis and subsequent reacylation back to CL (Zachman et al. 2010, Malhotra et al. 2009, Xu et al. 2003, Taylor & Hatch 2009, Cao et al. 2004, Zhao et al. 2009, Buckland et al. 1998).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 2** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P40939	Trifunctional enzyme subunit alpha, mitochondrial	HADH HADHA	view
P47712	Cytosolic phospholipase A2	CPLA2 PLA2G4 PLA2G4A	view

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