Hydrolysis of LPC

Summary
Organism
Homo sapiens (human)
Reactome
R-HSA-1483115
PubChem
R-HSA-1483115
Description
  • Lysophosphatidylcholine (LPC) is hydrolyzed by phospholipases to produce glycerophosphocholine (GPCho) which is in turn hydrolyzed by glycerophosphocholine phosphodiesterase to produce choline (Cho) and glycerol-3-phosphate (G3P) (Yamashita et al. 2009, Yamashita et al. 2005, Ghomashchi et al. 2010).
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Displaying all 3 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P47712 Cytosolic phospholipase A2
  • CPLA2
  • PLA2G4
  • PLA2G4A
view
Q6P4A8 Lysosomal leucine aminopeptidase
  • Lylap
  • PLBD1
view
Q8NCC3 Lysosomal phospholipase A and acyltransferase
  • LYPLA3
  • PLA2G15
  • UNQ341/PRO540
view
Displaying 1 entry
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_003205 Q9NPB8 Glycerophosphocholine phosphodiesterase GPCPD1 view

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026