NOD1/2 Signaling Pathway

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
IKK complexADPATPp-S177,S181-IKKB:IKKA:NEMOPAMP:NOD oligomer:K63-polyUb-RIP2:NEMOK63polyUbPAMP:NOD oligomer:RIP2:NEMONOD1NOD1:iE-DAPiE-DAPMDPMDP:NOD2NOD2NOD1:iE-DAP oligomerMDP:NOD2 oligomerRIP2PAMP:NOD oligomer:RIP2PAMP:NOD oligomerNEMOPAMP:NOD oligomer:RIP2:K63-Ub-K285-NEMOPAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:TAK1 complexTAK1 complexPAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complexp-S207,T211-MKK6MKK6Long prodomain caspasesNOD1:iE-DAP:Long prodomain caspasesPAMP:NOD oligomer:RIP2:CARD9CARD9p38 MAPKPhospho-p38 MAPKAAMPAAMP:NOD2
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025