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ARMS-mediated activation

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-170984

PubChem

R-HSA-170984

Description

ARMS (Ankyrin-Rich Membrane Spanning/Kidins 220) is a 220kD tetraspanning adaptor protein which becomes rapidly tyrosine phosphorylated by active Trk receptors. ARMS is another adaptor protein which is involved in the activation of Rap1 and the subsequent prolonged activation of the MAPK cascade.

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 4** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P01138	Beta-nerve growth factor	NGF NGFB	view
P04629	High affinity nerve growth factor receptor	MTC NTRK1 TRK TRKA	view
P46108	Adapter molecule crk	CRK	view
Q9ULH0	Kinase D-interacting substrate of 220 kDa	ARMS KIAA1250 KIDINS220	view

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