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APC/C:Cdc20 mediated degradation of Cyclin B

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-174048

PubChem

R-HSA-174048

Description

The degradation of cyclin B1, which appears to occur at the mitotic spindle, is delayed until the metaphase /anaphase transition by the spindle assembly checkpoint and is required in order for sister chromatids to separate (Geley et al. 2001;Hagting et al, 2002).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 7** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P30260	Cell division cycle protein 27 homolog	ANAPC3 CDC27 D0S1430E D17S978E	view
P62979	Ubiquitin-ribosomal protein eS31 fusion protein	RPS27A UBA80 UBCEP1	view
P62987	Ubiquitin-ribosomal protein eL40 fusion protein	UBA52 UBCEP2	view
Q13042	Cell division cycle protein 16 homolog	ANAPC6 CDC16	view
Q9H1A4	Anaphase-promoting complex subunit 1	ANAPC1 TSG24	view
Q9UJX2	Cell division cycle protein 23 homolog	ANAPC8 CDC23	view
Q9UJX3	Anaphase-promoting complex subunit 7	ANAPC7 APC7	view

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