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Synthesis of IP3 and IP4 in the cytosol

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-1855204

PubChem

R-HSA-1855204

Description

An array of inositol trisphosphate (IP3) and tetrakisphosphate (IP4) molecules are synthesised by the action of various kinases and phosphatases in the cytosol (Irvine & Schell 2001, Bunney & Katan 2010).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 16 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O15357	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2	INPPL1 SHIP2	view
O43426	Synaptojanin-1	KIAA0910 SYNJ1	view
O75038	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2	KIAA0450 PLCH2 PLCL4	view
P19174	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	PLC1 PLCG1	view
P32019	Type II inositol 1,4,5-trisphosphate 5-phosphatase	INPP5B OCRL2	view
P51178	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1	PLCD1	view
P60484	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	MMAC1 PTEN TEP1	view
Q00722	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2	PLCB2	view
Q01968	Inositol polyphosphate 5-phosphatase OCRL	OCRL OCRL1	view
Q01970	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3	PLCB3	view

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