Vasopressin-like receptors

Summary
Organism
Homo sapiens (human)
Reactome
R-HSA-388479
PubChem
R-HSA-388479
Description
  • The vasopressins are peptide hormones consisting of nine amino acids (nonapeptides). They include arginine vasopressin (AVP; anti-diuretic hormone, ADH) and oxytocin. They are synthesized in the hypothalamus from a precursor and released from stores in the posterior pituitary into the blood stream. One of the most important roles of vasopressins is the regulation of water retention in the body. Oxytocin is important in uterine contraction during birth. The vasopressins act via AVP and oxytocin receptors. These are connected to G proteins which act as second messengers and convey the signal inside the cell.
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Displaying all 5 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P01185 Vasopressin-neurophysin 2-copeptin
  • ARVP
  • AVP
  • VP
view
P30518 Vasopressin V2 receptor
  • ADHR
  • AVPR2
  • DIR
  • DIR3
  • V2R
view
P30559 Oxytocin receptor
  • OXTR
view
P37288 Vasopressin V1a receptor
  • AVPR1
  • AVPR1A
view
P47901 Vasopressin V1b receptor
  • AVPR1B
  • AVPR3
  • VPR3
view

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026