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mitochondrial fatty acid beta-oxidation of unsaturated fatty acids

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-77288

PubChem

R-HSA-77288

Description

The complete beta-oxidation spiral produces and consumes intermediates with a trans configuration. Mitochondrial beta-oxidation of unsaturated fatty acids leads to intermediates not compatible with the four enzymatic steps responsible for the beta-oxidation of saturated fatty acids. Unsaturated fatty acids that have bonds in the cis configuration require three separate enzymatic steps to prepare these molecules for the beta-oxidation pathway. The further processing of these intermediates requires additional enzymes, depending on the position of the double bonds in the original fatty acids. Described here is the beta-oxidation of linoleoyl-CoA.

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 2** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P11310	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial	ACADM	view
P40939	Trifunctional enzyme subunit alpha, mitochondrial	HADH HADHA	view

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