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Beta oxidation of palmitoyl-CoA to myristoyl-CoA

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-77305

PubChem

R-HSA-77305

Description

This first pass through the beta-oxidation spiral starts with the saturated fatty acid palmitoyl-CoA and produces myristoyl-CoA. Four enzymatic steps are required, starting with VLCAD CoA dehydrogenase (Very Long Chain) activity, followed by three enzymatic steps, enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and ketoacyl-CoA thiolase activities, all present in the mitochondrial membrane associated trifunctional protein.

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 2** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P40939	Trifunctional enzyme subunit alpha, mitochondrial	HADH HADHA	view
P49748	Very long-chain acyl-CoA dehydrogenase, mitochondrial	ACADVL VLCAD	view

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