Reuptake of GABA

Summary
Organism
Homo sapiens (human)
Reactome
R-HSA-888593
PubChem
R-HSA-888593
Description
  • Reuptake of GABA from the synapse terminates the action of GABA thus regulating GABA action. GABA taken up from the synapse into the neurons is reused for synaptic loading. GABA taken up by astrocytes is degraded into C02 and glutamine. Glutamine is transported into the neurons for glutamate and GABA synthesis.
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P30531 Sodium- and chloride-dependent GABA transporter 1
  • GABATR
  • GABT1
  • GAT1
  • SLC6A1
view
P48065 Sodium- and chloride-dependent betaine transporter
  • BGT1
  • SLC6A12
view
P48066 Sodium- and chloride-dependent GABA transporter 3
  • GABT3
  • GAT3
  • SLC6A11
view
Q9NSD5 Sodium- and chloride-dependent GABA transporter 2
  • GAT2
  • SLC6A13
view

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026