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DAG1 core M1 glycosylations

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-8932506

PubChem

R-HSA-8932506

Description

Protein-linked O-mannose glycans are initiated by the covalent attachment of mannose to serine and threonine residues in the protein via alpha-linkages. Core M1 glycans consist of all O-mannose glycans in which O-mannose is extended with beta-1,2-linked N-acetylglucosamine (GlcNAc) but not with beta-1,6-linked GlcNAc. M1 structures do not directly bind key extracellular components but are essential as precursors for M2 structures, and they support the maturation of M3 glycans (Praissman & Wells 2014; Endo, 2019).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 3** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
Q14118	Dystroglycan 1	DAG1	view
Q9UKY4	Protein O-mannosyl-transferase 2	POMT2	view
Q9Y6A1	Protein O-mannosyl-transferase 1	POMT1	view

Displaying 1 entry
GlyCosmos Lectin	UniProt ID	Lectin Name	Pathway Viewer
GL_000985	Q8WZA1	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	view

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