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Competing endogenous RNAs (ceRNAs) regulate PTEN translation

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-8948700

PubChem

R-HSA-8948700

Description

Coding and non-coding RNAs can prevent microRNAs from binding to PTEN mRNA. These RNAs are termed competing endogenous RNAs or ceRNAs. Transcripts of the pseudogene PTENP1 and mRNAs transcribed from SERINC1, VAPA and CNOT6L genes exhibit this activity (Poliseno et al. 2010, Tay et al. 2011, Tay et al. 2014). SERINC1 mRNA will be annotated in this context when additional experimental details become available.

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 7** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
Q8NDV7	Trinucleotide repeat-containing gene 6A protein	CAGH26 KIAA1460 TNRC6 TNRC6A	view
Q9H9G7	Protein argonaute-3	AGO3 EIF2C3	view
Q9HCE1	Helicase MOV-10	KIAA1631 MOV10	view
Q9HCJ0	Trinucleotide repeat-containing gene 6C protein	KIAA1582 TNRC6C	view
Q9UKV8	Protein argonaute-2	AGO2 EIF2C2	view
Q9UL18	Protein argonaute-1	AGO1 EIF2C1	view
Q9UPQ9	Trinucleotide repeat-containing gene 6B protein	KIAA1093 TNRC6B	view

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