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Lipophagy

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-9613354

PubChem

R-HSA-9613354

Description

Triglycerides stored in lipid droplets are hydrolysed under nutrient starvation to release fatty acids for energy. The content of lipid droplets may vary but they are all coated with a protective protein called perilipin. When this protein is degraded, lipid droplets associate with autophagic components and breakdown into fatty acids (Ward C et al. 2016, Schulze R J et al. 2017). This process is termed as lipophagy (Singh R et al. 2009).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 5** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O60664	Perilipin-3	M6PRBP1 PLIN3 TIP47	view
P11142	Heat shock cognate 71 kDa protein	HSC70 HSP73 HSPA10 HSPA8	view
P54646	5'-AMP-activated protein kinase catalytic subunit alpha-2	AMPK AMPK2 PRKAA2	view
Q99541	Perilipin-2	ADFP PLIN2	view
Q9UGJ0	5'-AMP-activated protein kinase subunit gamma-2	PRKAG2	view

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