Suppression of apoptosis

Summary
Organism
Homo sapiens (human)
Reactome
R-HSA-9635465
PubChem
R-HSA-9635465
Description
  • In order to survive and grow within the phagocyte, Mtb has to inhibit programmed cell death. Several proteins are secreted by Mtb that block different pathways leading to complete arrest of apoptosis (Moraco & Kornfeld 2014).
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P08311 Cathepsin G
  • CTSG
view
P23246 Splicing factor, proline- and glutamine-rich
  • PSF
  • SFPQ
view
P49840 Glycogen synthase kinase-3 alpha
  • GSK3A
view
Q63HN8 E3 ubiquitin-protein ligase RNF213
  • ALO17
  • C17orf27
  • KIAA1554
  • KIAA1618
  • MYSTR
  • RNF213
view

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026