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Modulation by Mtb of host immune system

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-9637628

PubChem

R-HSA-9637628

Description

Mtb enhances its chances for being taken up by a phagocyte by blocking adaptive immune responses, as well as other innate immune system responses. Components of the bacterial cell wall also specifically promote phagocytosis via both the opsonic pathway and the presentation of adhesins (Esparza et al. 2015).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 5** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O60603	Toll-like receptor 2	TIL4 TLR2	view
P22897	Macrophage mannose receptor 1	CLEC13D CLEC13DL MRC1 MRC1L1	view
P61769	Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]	B2M CDABP0092 HDCMA22P	view
P62979	Ubiquitin-ribosomal protein eS31 fusion protein	RPS27A UBA80 UBCEP1	view
P62987	Ubiquitin-ribosomal protein eL40 fusion protein	UBA52 UBCEP2	view

Displaying **all 2** entries
GlyCosmos Lectin	UniProt ID	Lectin Name	Pathway Viewer
GL_002045	P22897	Macrophage mannose receptor 1	view
GL_005335	P61769	Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]	view

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