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LTC4-CYSLTR mediated IL4 production

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-9664535

PubChem

R-HSA-9664535

Description

The Leukotriene C4 (LTC4) is a metabolite of arachidonic acid that can be produced intracellularly or extracellularly. LTC4 binds an unidentified, intracellular cysLTR. Signalling downstream LTC4 cysLTR binding has been associated with the production of IL4, independent of the GPCR associated heterotrimeric protein Gq (Bandeira Melo et al. 2002).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 6** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P16444	Dipeptidase 1	DPEP1 MDP RDP	view
P19440	Glutathione hydrolase 1 proenzyme	GGT GGT1	view
P36269	Glutathione hydrolase 5 proenzyme	GGT5 GGTLA1	view
Q9H4A9	Dipeptidase 2	DPEP2 UNQ284/PRO323	view
Q9NS75	Cysteinyl leukotriene receptor 2	CYSLT2 CYSLT2R CYSLTR2 PSEC0146	view
Q9Y271	Cysteinyl leukotriene receptor 1	CYSLT1 CYSLTR1	view

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