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TGFBR3 regulates activin signaling

Summary

Organism

Homo sapiens (human)

Reactome

R-HSA-9839406

PubChem

R-HSA-9839406

Description

This subpathway describes the regulation of activin signaling by TGFBR3. TGFBR3 binds with Inhibin A, which is also a ligand for TGFBR3 and inhibits activin/BMP signaling by binding competititively to ACVR2A receptor and BMPRII (Esparza-Lopez et al., 2001, Lewis et al., 2000, Wiater et al., 2003).

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 4** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P05111	Inhibin alpha chain	INHA	view
P08476	Inhibin beta A chain	INHBA	view
P27037	Activin receptor type-2A	ACVR2 ACVR2A	view
Q03167	Transforming growth factor beta receptor type 3	TGFBR3	view

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