GlyCosmos Portal

Submissions

JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1

Summary

Organism

Mus musculus (house mouse)

Reactome

R-MMU-450321

PubChem

R-MMU-450321

Description

This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 6** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
P0CG49	Polyubiquitin-B [Cleaved into: Ubiquitin]	Ubb	view
P47809	Dual specificity mitogen-activated protein kinase kinase 4	Jnkk1 Map2k4 Mek4 Mkk4 Prkmk4 Sek1 Serk1 Skk1	view
Q571K4	TGF-beta-activated kinase 1 and MAP3K7-binding protein 3	Kiaa4135 Map3k7ip3 Tab3	view
Q62073	Mitogen-activated protein kinase kinase kinase 7	Map3k7 Tak1	view
Q8CF89	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1	Map3k7ip1 Tab1	view
Q99K90	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2	Kiaa0733 Map3k7ip2 Tab2	view

If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".

About Release Notes Help Feedback

Click here to visit the beta site.