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RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function

Summary

Organism

Mus musculus (house mouse)

Reactome

R-MMU-8936459

PubChem

R-MMU-8936459

Description

This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 22 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
B2RWS6	Histone acetyltransferase p300	Ep300 P300	view
E9PYH6	Histone-lysine N-methyltransferase SETD1A	Setd1a	view
O08550	Histone-lysine N-methyltransferase 2B	Kmt2b Mll2 Trx2 Wbp7	view
O09106	Histone deacetylase 1	Hdac1	view
P10853	Histone H2B type 1-F/J/L	H2b-f H2b-j H2b-l H2b-n H2bc7; H2bc11; H2bc13; H2bc15 Hist1h2bf Hist1h2bj Hist1h2bl Hist1h2bn	view
P55200	Histone-lysine N-methyltransferase 2A	All1 Hrx Kmt2a Mll Mll1	view
P62806	Histone H4	H4-12 H4-53 H4c1; H4c2; H4c3; H4c4; H4c6; H4c8; H4c9; H4c11; H4c12; Hist1h4m; H4c14; H4c16 H4f16 Hist1h4a Hist1h4b Hist1h4c Hist1h4d Hist1h4f Hist1h4h Hist1h4i Hist1h4j Hist1h4k Hist2h4 Hist2h4a Hist4h4	view
Q60520	Paired amphipathic helix protein Sin3a	Kiaa4126 Sin3a	view
Q64475	Histone H2B type 1-B	H2bc3 Hist1h2bb	view
Q64478	Histone H2B type 1-H	H2bc9 Hist1h2bh	view

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