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ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA

Summary

Organism

Mus musculus (house mouse)

Reactome

R-MMU-9954716

PubChem

R-MMU-9954716

Description

This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 20 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O55142	Large ribosomal subunit protein eL33	Rpl35a	view
P0CG49	Polyubiquitin-B [Cleaved into: Ubiquitin]	Ubb	view
P19253	Large ribosomal subunit protein uL13	P198 Rpl13a Tstap198-7	view
P25444	Small ribosomal subunit protein uS5	Llrep3 Rps2 Rps4	view
P35979	Large ribosomal subunit protein uL11	Rpl12	view
P47911	Large ribosomal subunit protein eL6	Rpl6	view
P47915	Large ribosomal subunit protein eL29	Rpl29 Rpl43	view
P61255	Large ribosomal subunit protein uL24	Rpl26	view
P62264	Small ribosomal subunit protein uS11	Rps14	view
P62702	Small ribosomal subunit protein eS4	Rps4 Rps4x	view

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