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WNT5A-dependent internalization of FZD2, FZD5 and ROR2

Summary

Organism

Rattus norvegicus (Norway rat)

Reactome

R-RNO-5140745

PubChem

R-RNO-5140745

Description

This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying **all 6** entries
UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
A0A8I6A4J2	AP-2 complex subunit alpha	Ap2a1	view
P18484	AP-2 complex subunit alpha-2	Adtab Ap2a2	view
P62944	AP-2 complex subunit beta	Ap2b1 Clapb1	view
Q08464	Frizzled-2	Fzd2	view
Q8CHL0	Frizzled-5	Fzd5	view
Q9QXQ7	Protein Wnt-5a	Wnt-5a Wnt5a	view

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